HAMAP rule MF_01460

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01460
Accession	MF_01460
Dates	01-NOV-2010 (Created) 13-JUL-2026 (Last updated, Version )
Name	Chrphore_lyase_CpxT
Scope(s)	Bacteria Cyanobacteriota
Template(s)	B1XI94 (CPCT_PICP2); Q8YLF9 (CPCT1_NOSS1); P0DYI2 (CPET_GUITH); [ Recover all ]
Triggered by	HAMAP; MF_01460 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CPXT
Protein name	RecName: Full=Chromophore lyase CpcT/CpeT; EC=4.4.1.-;
Gene name	Name=cpcT;

Comments [?]

FUNCTION	Catalyzes the site-selective attachment of a phycobilin chromophore to Cys residue(s) of phycobiliproteins. Multiple chromophorylated PBPs assemble into phycobilisomes (PBS), large complexes that harvest light in Cyanobacteriota and red algae.
SUBUNIT	Monomer at low concentration, dimer at higher concentrations or in presence of chromophore; dimer dissociation, perhaps upon interaction with target protein, is probably required for catalysis.
SUBCELLULAR LOCATION	Cytoplasm.
DOMAIN	Has a conical, goblet-shaped beta-barrel with 10 anti-parallel beta-strands; a loop from one subunit partially blocks the beta-barrel in the other subunit, which partially protects chromophore binding.
SIMILARITY	Belongs to the CpcT/CpeT biliprotein lyase family.

Keywords [?]

Gene Ontology [?]

GO:0017006; Biological process:protein-tetrapyrrole linkage

Cross-references [?]

Pfam	PF06206; CpeT; 1;

Features [?]

From: CPCT1_NOSS1 (Q8YLF9)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

/note="Proton donor"

ACT_SITE

163

/note="Proton donor"

DISULFID

116

137

Disulfide

C-x*-C

Additional information [?]