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HAMAP rule MF_01461

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General rule information [?]

Accession MF_01461
Dates 11-APR-2011 (Created)
17-FEB-2023 (Last updated, Version 8)
Name EcfT
Scope(s) Bacteria
Template(s) A2RI03 (ECFT_LACLM); Q035B4 (ECFT_LACP3); Q03ZL4 (ECFT_LEUMM); [ Recover all ]
Triggered by HAMAP; MF_01461 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ECFT
Protein name RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT;
                 Short=ECF transporter T component EcfT;
Gene name Name=ecfT;

Comments [?]

FUNCTIONTransmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
SUBUNITForms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the energy-coupling factor EcfT family.

Keywords [?]

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF02361; CbiQ; 1;
General Transmembrane; -; 4-6;

Features [?]

Additional information [?]

Size range 260-285 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments For further discussion see PubMed=18931129; DOI=10.1128/JB.01208-08; Rodionov D.A., Hebbeln P., Eudes A., ter Beek J., Rodionova I.A., Erkens G.B., Slotboom D.J., Gelfand M.S., Osterman A.L., Hanson A.D., Eitinger T.; "A novel class of modular transporters for vitamins in prokaryotes."; J. Bacteriol. 191:42-51(2009). The subunit composition has been determined to be 2S:2T:A1:A2 PMID:23359690.

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