HAMAP rule MF_01461

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01461
Accession	MF_01461
Dates	11-APR-2011 (Created) 17-FEB-2023 (Last updated, Version 9)
Name	EcfT
Scope(s)	Bacteria Bacillota Synergistota
Template(s)	A2RI03; Q035B4; Q03ZL4; [ Recover all ]
Triggered by	HAMAP; MF_01461 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ECFT
Protein name	RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT; Short=ECF transporter T component EcfT;
Gene name	Name=ecfT;

Comments [?]

FUNCTION	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
SUBUNIT	Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the energy-coupling factor EcfT family.

Keywords [?]

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam	PF02361; CbiQ; 1;
General	Transmembrane; -; 4-6;

Features [?]

Additional information [?]

Size range	260-285 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	For further discussion see PubMed=18931129; DOI=10.1128/JB.01208-08; Rodionov D.A., Hebbeln P., Eudes A., ter Beek J., Rodionova I.A., Erkens G.B., Slotboom D.J., Gelfand M.S., Osterman A.L., Hanson A.D., Eitinger T.; "A novel class of modular transporters for vitamins in prokaryotes."; J. Bacteriol. 191:42-51(2009). The subunit composition has been determined to be 2S:2T:A1:A2 PMID:23359690.