HAMAP rule MF_01461
General rule information
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| Accession | MF_01461 |
| Dates | 11-APR-2011 (Created)
17-FEB-2023 (Last updated, Version 8) |
| Name | EcfT |
| Scope(s) |
Bacteria Bacillota Synergistota |
| Template(s) | A2RI03 (ECFT_LACLM); Q035B4 (ECFT_LACP3); Q03ZL4 (ECFT_LEUMM); [ Recover all ] |
| Triggered by |
HAMAP; MF_01461 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ECFT |
| Protein name | RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT; Short=ECF transporter T component EcfT; |
| Gene name | Name=ecfT; |
Comments
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| FUNCTION | Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. |
| SUBUNIT | Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component). |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the energy-coupling factor EcfT family. |
Keywords
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Gene Ontology
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| GO:0022857; Molecular function:transmembrane transporter activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02361; CbiQ; 1; |
| General | Transmembrane; -; 4-6; |
Features
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Additional information
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| Size range | 260-285 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | For further discussion see PubMed=18931129; DOI=10.1128/JB.01208-08; Rodionov D.A., Hebbeln P., Eudes A., ter Beek J., Rodionova I.A., Erkens G.B., Slotboom D.J., Gelfand M.S., Osterman A.L., Hanson A.D., Eitinger T.; "A novel class of modular transporters for vitamins in prokaryotes."; J. Bacteriol. 191:42-51(2009). The subunit composition has been determined to be 2S:2T:A1:A2 PMID:23359690. |