HAMAP rule MF_01462

General rule information [?]

Accession	MF_01462
Dates	7-JUN-2011 (Created) 1-MAR-2024 (Last updated, Version 8)
Name	CbiM
Scope(s)	Bacteria Archaea
Template(s)	Q05594 (CBIM_SALTY); D5AUZ9 (CBIM_RHOCB); [ Recover all ]
Triggered by	HAMAP; MF_01462 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CBIM
case <OC:Bacteria>
Protein name	RecName: Full=Cobalt transport protein CbiM; AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM; Short=ECF transporter S component CbiM;
else case <OC:Archaea>
Protein name	RecName: Full=Putative cobalt transport protein CbiM; AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM; Short=ECF transporter S component CbiM;
end case
Gene name	Name=cbiM;

Comments [?]

FUNCTION	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
PATHWAY	Cofactor biosynthesis; adenosylcobalamin biosynthesis.
SUBUNIT	Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
end case
SIMILARITY	Belongs to the CbiM family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Cobalamin biosynthesis
Cobalt
Cobalt transport
Ion transport
Membrane
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0015087; Molecular function:cobalt ion transmembrane transporter activity

GO:0006824; Biological process:cobalt ion transport

GO:0009236; Biological process:cobalamin biosynthetic process

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]

Size range	215-261 amino acids
Related rules	None
Fusion	Nter: None Cter: <cbiQ>; <Unknown>
Comments	In Pseudomonadota is part of a dedicated cobalt transporter; presumably also in other bacteria. In some organisms may have a signal sequence; the N-terminal sequence (M-H-x(3)-G-X-L) has been shown to be essential for function in Rhodobacter capsulatus.