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Annotation rule MF_01462
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General rule information [?]

Accession MF_01462
Dates 7-JUN-2011 (Created)
19-NOV-2019 (Last updated, Version 5)
Name CbiM
Scope
Bacteria
Archaea
Templates Q05594 (CBIM_SALTY); D5AUZ9 (CBIM_RHOCB): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CBIM
case <OC:Bacteria>
Protein name
RecName: Full=Cobalt transport protein CbiM;
AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM;
Short=ECF transporter S component CbiM;
else case <OC:Archaea>
Protein name
RecName: Full=Putative cobalt transport protein CbiM;
AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM;
Short=ECF transporter S component CbiM;
end case
Gene name
cbiM

Comments [?]

Function Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
Pathway Cofactor biosynthesis; adenosylcobalamin biosynthesis.
Subunit Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the CbiM family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Cobalamin biosynthesis
Cobalt
Cobalt transport
Ion transport
Membrane
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0015087; Molecular function: cobalt ion transmembrane transporter activity.
GO:0006824; Biological process: cobalt ion transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF01891; CbiM; 1;
TIGRFAMs TIGR00123; CbiM; 1;

Computed features [?]

General Signal; -; 0-1; trigger=yes;
Transmembrane; -; 5-8; trigger=yes;

Additional information [?]

case <OC:Deltaproteobacteria>
Size range 215-346 amino acids
else
Size range 215-261 amino acids
end case
Related rules None
Fusion Nter: None; Cter: <cbiQ>, <Unknown>
Comments In Proteobacteria is part of a dedicated cobalt transporter; presumably also in other bacteria. In some organisms may have a signal sequence; the N-terminal sequence (M-H-x(3)-G-X-L) has been shown to be essential for function in Rhodobacter capsulatus.


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