HAMAP rule MF_01468
General rule information
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Accession | MF_01468 |
Dates | 24-JAN-2012 (Created) 17-FEB-2023 (Last updated, Version 8) |
Name | RNase_Mini_III |
Scope | Bacteria; Cyanobacteriota
Bacteria; Bacillota
Bacteria; Fusobacteriota
Bacteria; Mycoplasmatota
Bacteria; Thermotogae |
Templates | O31418 (MRNC_BACSU); Q81J58 (MRNC_BACCR): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. |
Cofactor | Mg(2+) |
Subunit | Homodimer. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the MrnC RNase family. |
Keywords
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Cytoplasm
Endonuclease
Hydrolase
Magnesium
Nuclease
Ribosome biogenesis
RNA-binding
rRNA processing
rRNA-binding
Endonuclease
Hydrolase
Magnesium
Nuclease
Ribosome biogenesis
RNA-binding
rRNA processing
rRNA-binding
Gene Ontology
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GO:0019843; Molecular function: rRNA binding.
GO:0006364; Biological process: rRNA processing.
GO:0042254; Biological process: ribosome biogenesis.
GO:0005737; Cellular component: cytoplasm.
GO:0006364; Biological process: rRNA processing.
GO:0042254; Biological process: ribosome biogenesis.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF00636; Ribonuclease_3; 1; |
PIRSF | PIRSF005520; UCP005520; 1; |
Features
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From: MRNC_BACSU (O31418) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 23 | 23 | D |
Additional information
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Size range | 110-170 amino acids |
Related rules | None |
Fusion | None |
Comments | Fusobacteriota (FUSNN and ILYPC) have F or Y instead of conserved E in a possibly catalytically important active site and are considered atypical. |