HAMAP rule MF_01468

General rule information [?]

Accession	MF_01468
Dates	24-JAN-2012 (Created) 17-FEB-2023 (Last updated, Version 8)

Name	RNase_Mini_III

Scope

Bacteria; Cyanobacteriota

Bacteria; Bacillota

Bacteria; Fusobacteriota

Bacteria; Mycoplasmatota

Bacteria; Thermotogae

Templates

O31418 (MRNC_BACSU); Q81J58 (MRNC_BACCR): [Recover all]

Triggered by

HAMAP; MF_01468 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MRNC

Protein name

RecName:		Full=Mini-ribonuclease 3;
		Short=Mini-RNase 3;
		Short=Mini-3;
		EC 3.1.26.-;
AltName:		Full=Mini-RNase III;
		Short=Mini-III;

Gene name

mrnC

Comments [?]

Function	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
Cofactor	Mg(2+)
Subunit	Homodimer.
Subcellular location	Cytoplasm.
Similarity	Belongs to the MrnC RNase family.

Keywords [?]

Cytoplasm
Endonuclease
Hydrolase
Magnesium
Nuclease
Ribosome biogenesis
RNA-binding
rRNA processing
rRNA-binding

Gene Ontology [?]

GO:0019843; Molecular function: rRNA binding.
GO:0006364; Biological process: rRNA processing.
GO:0042254; Biological process: ribosome biogenesis.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00636; Ribonuclease_3; 1;
PIRSF	PIRSF005520; UCP005520; 1;

Features [?]

From: MRNC_BACSU (O31418)

Key From To Description Tag Condition FTGroup

ACT_SITE 23 23 D

Additional information [?]

Size range	110-170 amino acids
Related rules	None
Fusion	None
Comments	Fusobacteriota (FUSNN and ILYPC) have F or Y instead of conserved E in a possibly catalytically important active site and are considered atypical.

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