HAMAP rule MF_01468

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01468
Accession	MF_01468
Dates	24-JAN-2012 (Created) 17-FEB-2023 (Last updated, Version 9)
Name	RNase_Mini_III
Scope(s)	Bacteria Cyanobacteriota Bacillota Fusobacteriota Mycoplasmatota Thermotogae
Template(s)	O31418; Q81J58; [ Recover all ]
Triggered by	HAMAP; MF_01468 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MRNC
Protein name	RecName: Full=Mini-ribonuclease 3; Short=Mini-RNase 3; Short=Mini-3; EC=3.1.26.-; AltName: Full=Mini-RNase III; Short=Mini-III;
Gene name	Name=mrnC;

Comments [?]

FUNCTION	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
COFACTOR	Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
SUBUNIT	Homodimer.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the MrnC RNase family.

Keywords [?]

Gene Ontology [?]

GO:0019843; Molecular function:rRNA binding

GO:0006364; Biological process:rRNA processing

GO:0042254; Biological process:ribosome biogenesis

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF00636; Ribonuclease_3; 1;
PIRSF	PIRSF005520; UCP005520; 1;

Features [?]

From: MRNC_BACSU (O31418)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

Additional information [?]

Size range	110-170 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	Fusobacteriota (FUSNN and ILYPC) have F or Y instead of conserved E in a possibly catalytically important active site and are considered atypical.