HAMAP rule MF_01468
General rule information
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| Accession | MF_01468 |
| Dates | 24-JAN-2012 (Created)
17-FEB-2023 (Last updated, Version 8) |
| Name | RNase_Mini_III |
| Scope(s) |
Bacteria Cyanobacteriota Bacillota Fusobacteriota Mycoplasmatota Thermotogae |
| Template(s) | O31418 (MRNC_BACSU); Q81J58 (MRNC_BACCR); [ Recover all ] |
| Triggered by |
HAMAP; MF_01468 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MRNC |
| Protein name | RecName: Full=Mini-ribonuclease 3; Short=Mini-RNase 3; Short=Mini-3; EC=3.1.26.-; AltName: Full=Mini-RNase III; Short=Mini-III; |
| Gene name | Name=mrnC; |
Comments
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| FUNCTION | Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the MrnC RNase family. |
Keywords
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| Cytoplasm |
| Endonuclease |
| Hydrolase |
| Magnesium |
| Nuclease |
| Ribosome biogenesis |
| RNA-binding |
| rRNA processing |
| rRNA-binding |
Gene Ontology
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| GO:0019843; Molecular function:rRNA binding |
| GO:0006364; Biological process:rRNA processing |
| GO:0042254; Biological process:ribosome biogenesis |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00636; Ribonuclease_3; 1; |
| PIRSF | PIRSF005520; UCP005520; 1; |
Features
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| From: MRNC_BACSU (O31418) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 23 | 23 | D | |||||||||
Additional information
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| Size range | 110-170 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Fusobacteriota (FUSNN and ILYPC) have F or Y instead of conserved E in a possibly catalytically important active site and are considered atypical. |