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HAMAP rule MF_01477

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General rule information [?]

Accession MF_01477
Dates 16-AUG-2012 (Created)
1-JUN-2023 (Last updated, Version 8)
Name Iojap_RsfS
Templates P0AAT6 (IOJAP_ECOLI); Q96EH3 (MASU1_HUMAN); Q41822 (IOJAP_MAIZE): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribosomal silencing factor RsfS;
Gene name

Comments [?]

Function Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
Subunit Interacts with ribosomal protein uL14 (rplN).
Subcellular location Cytoplasm.
Similarity Belongs to the Iojap/RsfS family.

Keywords [?]

Gene Ontology [?]

GO:0042256; Biological process: cytosolic ribosome assembly.
GO:0090071; Biological process: negative regulation of ribosome biogenesis.
GO:0017148; Biological process: negative regulation of translation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02410; Oligomerisation; 1;
NCBIfam TIGR00090; Iojap_ybeB; 1;

Additional information [?]

Size range 102-234 amino acids
Related rules None
Fusion None
Comments Eukaryotic orthologs act in mitochondria and plastids. In human mitochondria they prevent association of the ribosomal subunits and affect translation in an uncharacterized fashion in maize plastids.