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HAMAP rule MF_01477

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General rule information [?]

Accession MF_01477
Dates 16-AUG-2012 (Created)
1-JUN-2023 (Last updated, Version 8)
Name Iojap_RsfS
Scope(s) Bacteria
Template(s) P0AAT6 (IOJAP_ECOLI); Q96EH3 (MASU1_HUMAN); Q41822 (IOJAP_MAIZE); [ Recover all ]
Triggered by HAMAP; MF_01477 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier IOJAP
Protein name RecName: Full=Ribosomal silencing factor RsfS;
Gene name Name=rsfS;

Comments [?]

FUNCTIONFunctions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
SUBUNITInteracts with ribosomal protein uL14 (rplN).
SIMILARITYBelongs to the Iojap/RsfS family.

Keywords [?]

Gene Ontology [?]

GO:0042256; Biological process:cytosolic ribosome assembly
GO:0090071; Biological process:negative regulation of ribosome biogenesis
GO:0017148; Biological process:negative regulation of translation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02410; Oligomerisation; 1;
NCBIfam TIGR00090; Iojap_ybeB; 1;

Features [?]

Additional information [?]

Size range 102-234 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Eukaryotic orthologs act in mitochondria and plastids. In human mitochondria they prevent association of the ribosomal subunits and affect translation in an uncharacterized fashion in maize plastids.

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