HAMAP rule MF_01483
General rule information
[?]
| Accession | MF_01483 |
| Dates | 23-JUL-2013 (Created)
13-JAN-2023 (Last updated, Version 11) |
| Name | RbpA |
| Scope(s) |
Bacteria Actinomycetota |
| Template(s) | P9WHJ5 (RBPA_MYCTU); Q9RKY0 (RBPA_STRCO); A0QZ11 (RBPA_MYCS2); [ Recover all ] |
| Triggered by |
HAMAP; MF_01483 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | RBPA |
| Protein name | RecName: Full=RNA polymerase-binding protein RbpA; |
| Gene name | Name=rbpA; |
Comments
[?]
| FUNCTION | Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. |
| case <FTGroup:1> | |
| COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Bind 1 Zn(2+) per subunit.; |
| end case | |
| SUBUNIT | Forms a complex with the RNAP catalytic core and with free principal sigma factors. |
| SIMILARITY | Belongs to the RNA polymerase-binding protein RbpA family. |
Keywords
[?]
| Transcription | |
| Transcription regulation | |
| case <FTGroup:1> | |
| Metal-binding | |
| Zinc | |
| end case | |
Gene Ontology
[?]
| GO:0001000; Molecular function:bacterial-type RNA polymerase core enzyme binding | |
| GO:0045893; Biological process:positive regulation of DNA-templated transcription | |
| case <FTGroup:1> | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
Cross-references
[?]
| Pfam | PF13397; DUF4109; 1; |
Features
[?]
| From: RBPA_STRCO (Q9RKY0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 34 | 34 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 38 | 38 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H | 1 | |||||||
| BINDING | 56 | 56 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 59 | 59 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
Additional information
[?]
| Size range | 95-214 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |