HAMAP rule MF_01483
General rule information
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| Accession | MF_01483 |
| Dates | 23-JUL-2013 (Created) 13-JAN-2023 (Last updated, Version 11) |
| Name | RbpA |
| Scope | Bacteria; Actinomycetota |
| Templates | P9WHJ5 (RBPA_MYCTU); Q9RKY0 (RBPA_STRCO); A0QZ11 (RBPA_MYCS2): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. |
case <FTGroup:1>
| Cofactor | Zn(2+) Note: Bind 1 Zn(2+) per subunit. |
end case
| Subunit | Forms a complex with the RNAP catalytic core and with free principal sigma factors. |
| Similarity | Belongs to the RNA polymerase-binding protein RbpA family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0001000; Molecular function: bacterial-type RNA polymerase core enzyme binding.
GO:0045893; Biological process: positive regulation of DNA-templated transcription.
GO:0045893; Biological process: positive regulation of DNA-templated transcription.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
Cross-references
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| Pfam | PF13397; DUF4109; 1; |
Features
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| From: RBPA_STRCO (Q9RKY0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING (Optional) | 34 | 34 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING (Optional) | 38 | 38 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | H | 1 | |||||||
| BINDING (Optional) | 56 | 56 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
| BINDING (Optional) | 59 | 59 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
Additional information
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| Size range | 95-214 amino acids |
| Related rules | None |
| Fusion | None |