HAMAP rule MF_01522

General rule information [?]

Accession	MF_01522
Dates	7-SEP-2004 (Created) 1-JUN-2023 (Last updated, Version 48)
Name	Kup
Scope(s)	Bacteria Archaea Methanomicrobia
Template(s)	P63183 (KUP_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01522 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	KUP
case <OC:Enterobacterales>
Protein name	RecName: Full=Low affinity potassium transport system protein Kup; AltName: Full=Kup system potassium uptake protein;
else
Protein name	RecName: Full=Probable potassium transport system protein Kup;
end case
Gene name	Name=kup;

Comments [?]

case <OC:Enterobacterales>
FUNCTION	Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.
else
FUNCTION	Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.
end case
CATALYTIC ACTIVITY	Reaction=H(+)(in) + K(+)(in) = H(+)(out) + K(+)(out); Xref=Rhea:RHEA:28490, ChEBI:CHEBI:15378, ChEBI:CHEBI:29103; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28492;
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
end case
SIMILARITY	Belongs to the HAK/KUP transporter (TC 2.A.72) family.

Keywords [?]

Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Ion transport
Membrane
Potassium
Potassium transport
Symport
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0015079; Molecular function:potassium ion transmembrane transporter activity

GO:0015293; Molecular function:symporter activity

GO:0006813; Biological process:potassium ion transport

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]