HAMAP rule MF_01522
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01522 |
| Accession | MF_01522 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 50) |
| Name | Kup |
| Scope(s) |
Bacteria Archaea Methanomicrobia |
| Template(s) | P63183; [ Recover all ] |
| Triggered by |
HAMAP; MF_01522 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | KUP |
| case <OC:Enterobacterales> | |
| Protein name | RecName: Full=Low affinity potassium transport system protein Kup; AltName: Full=Kup system potassium uptake protein; |
| else | |
| Protein name | RecName: Full=Probable potassium transport system protein Kup; |
| end case | |
| Gene name | Name=kup; |
Comments
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| case <OC:Enterobacterales> | |
| FUNCTION | Responsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. |
| else | |
| FUNCTION | Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=K(+)(in) + H(+)(in) = K(+)(out) + H(+)(out); Xref=Rhea:RHEA:28490, ChEBI:CHEBI:15378, ChEBI:CHEBI:29103; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28492; |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the HAK/KUP transporter (TC 2.A.72) family. |
Keywords
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| Cell membrane | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Ion transport | |
| Membrane | |
| Potassium | |
| Potassium transport | |
| Symport | |
| Transmembrane | |
| Transport | |
| Transmembrane helix | |
Gene Ontology
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| GO:0015079; Molecular function:potassium ion transmembrane transporter activity |
| GO:0015293; Molecular function:symporter activity |
| GO:0006813; Biological process:potassium ion transport |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02705; K_trans; 1; |
| NCBIfam | TIGR00794; Kup; 1; |
| General | Transmembrane; -; 11-13; |
Features
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Additional information
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| Size range | 603-684 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |