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HAMAP rule MF_01522

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General rule information [?]

Accession MF_01522
Dates 7-SEP-2004 (Created)
28-NOV-2023 (Last updated, Version 50)
Name Kup
Scope(s) Bacteria
Template(s) P63183 (KUP_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01522 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier KUP
case <OC:Enterobacterales>
Protein name RecName: Full=Low affinity potassium transport system protein Kup;
AltName: Full=Kup system potassium uptake protein;
Protein name RecName: Full=Probable potassium transport system protein Kup;
end case
Gene name Name=kup;

Comments [?]

case <OC:Enterobacterales>
FUNCTIONResponsible for the low-affinity transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.
FUNCTIONTransport of potassium into the cell. Likely operates as a K(+):H(+) symporter.
end case
CATALYTIC ACTIVITY Reaction=H(+)(in) + K(+)(in) = H(+)(out) + K(+)(out); Xref=Rhea:RHEA:28490, ChEBI:CHEBI:15378, ChEBI:CHEBI:29103; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28492;
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the HAK/KUP transporter (TC 2.A.72) family.

Keywords [?]

Gene Ontology [?]

GO:0015079; Molecular function:potassium ion transmembrane transporter activity
GO:0015293; Molecular function:symporter activity
GO:0006813; Biological process:potassium ion transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF02705; K_trans; 1;
NCBIfam TIGR00794; Kup; 1;
General Transmembrane; -; 11-13;

Features [?]

Additional information [?]

Size range 603-684 amino acids
Related rules None
Fusion Nter: None Cter: None

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