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Annotation rule MF_01530
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General rule information [?]

Accession MF_01530
Dates 14-FEB-2005 (Created)
19-NOV-2019 (Last updated, Version 27)
Name MFS_MdtL
Scope
Bacteria; Gammaproteobacteria
Template P31462 (MDTL_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MDTL
Protein name
RecName: Full=Multidrug resistance protein MdtL;
Gene name
mdtL

Comments [?]

case <OC:Escherichia>
Function Confers resistance to chloramphenicol.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.

Keywords [?]

case <OC:Escherichia>
Antibiotic resistance
end case
Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Membrane
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0022857; Molecular function: transmembrane transporter activity.
GO:0055085; Biological process: transmembrane transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF07690; MFS_1; 1;
PROSITE PS50850; MFS; 1;

Computed features [?]

General Transmembrane; -; 12; trigger=yes;

Additional information [?]

Size range 390-396 amino acids
Related rules None
Fusion None


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