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HAMAP rule MF_01530

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General rule information [?]

Accession MF_01530
Dates 14-FEB-2005 (Created)
19-NOV-2019 (Last updated, Version 27)
Name MFS_MdtL
Scope(s) Bacteria
Template(s) P31462 (MDTL_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01530 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MDTL
Protein name RecName: Full=Multidrug resistance protein MdtL;
Gene name Name=mdtL;

Comments [?]

case <OC:Escherichia>
FUNCTIONConfers resistance to chloramphenicol.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.

Keywords [?]

case <OC:Escherichia>
Antibiotic resistance
end case
Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Transmembrane helix

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity
GO:0055085; Biological process:transmembrane transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF07690; MFS_1; 1;
PROSITE PS50850; MFS; 1;
General Transmembrane; -; 12;

Features [?]

Additional information [?]

Size range 390-396 amino acids
Related rules None
Fusion Nter: None Cter: None

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