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HAMAP rule MF_01535

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General rule information [?]

Accession MF_01535
Dates 29-MAR-2005 (Created)
19-NOV-2022 (Last updated, Version 24)
Name Rhamnulokinase
Scope
Bacteria
Template P32171 (RHAB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RHAB
Protein name
RecName: Full=Rhamnulokinase;
Short=RhaB;
EC 2.7.1.5;
AltName: Full=Rhamnulose kinase;
AltName: Full=L-rhamnulose 1-kinase;
AltName: Full=ATP:L-rhamnulose phosphotransferase;
Gene name
rhaB

Comments [?]

Function Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
Catalytic activity RHEA:20117: ATP + L-rhamnulose = ADP + H(+) + L-rhamnulose 1-phosphate
EC 2.7.1.5
Cofactor Mg(2+)
Pathway Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3.
case <OC:Escherichia>
Subunit Monomer.
end case
Similarity Belongs to the rhamnulokinase family.

Keywords [?]

ATP-binding
Kinase
Magnesium
Nucleotide-binding
Rhamnose metabolism
Transferase
case <FT:9> or <FT:10> or <FT:11>
Disulfide bond
end case

Gene Ontology [?]

GO:0008993; Molecular function: rhamnulokinase activity.
GO:0019299; Biological process: rhamnose metabolic process.

Cross-references [?]

Pfam PF00370; FGGY_N; 1;
TIGRFAMs TIGR02627; Rhamnulo_kin; 1;

Features [?]

From: RHAB_ECOLI (P32171)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     13     17       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     A-[ST]-x(2)-R  
BINDING     236     238       /ligand="substrate     H-D-T  
ACT_SITE     237     237       Proton acceptor     D  
BINDING     83     83       /ligand="substrate     [GA]  
BINDING     259     259       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     T  
BINDING     296     296       /ligand="substrate     N  
BINDING     304     304       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     [QNE]  
BINDING     402     402       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G  
DISULFID     68     222             C-x*-C  
DISULFID     353     370             C-x*-C  
DISULFID     413     417             C-x*-C  

Additional information [?]

Size range 467-496 amino acids
Related rules None
Fusion Nter: None; Cter: MF_00541 (rhaA)


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