HAMAP logo

HAMAP rule MF_01535

Send feedback

General rule information [?]

Accession MF_01535
Dates 29-MAR-2005 (Created)
1-JUN-2023 (Last updated, Version 25)
Name Rhamnulokinase
Scope(s) Bacteria
Template(s) P32171 (RHAB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01535 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RHAB
Protein name RecName: Full=Rhamnulokinase;
AltName: Full=Rhamnulose kinase;
AltName: Full=L-rhamnulose 1-kinase;
AltName: Full=ATP:L-rhamnulose phosphotransferase;
Gene name Name=rhaB;

Comments [?]

FUNCTIONInvolved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
CATALYTIC ACTIVITY Reaction=ATP + L-rhamnulose = ADP + H(+) + L-rhamnulose 1-phosphate; Xref=Rhea:RHEA:20117, ChEBI:CHEBI:15378, ChEBI:CHEBI:17897, ChEBI:CHEBI:30616, ChEBI:CHEBI:58313, ChEBI:CHEBI:456216; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
PATHWAYCarbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3.
case <OC:Escherichia>
end case
SIMILARITYBelongs to the rhamnulokinase family.

Keywords [?]

Gene Ontology [?]

GO:0008993; Molecular function:rhamnulokinase activity
GO:0019299; Biological process:rhamnose metabolic process

Cross-references [?]

Pfam PF00370; FGGY_N; 1;
NCBIfam TIGR02627; Rhamnulo_kin; 1;

Features [?]

From: RHAB_ECOLI (P32171)
Key From To Description Tag Condition FTGroup
BINDING 13 17 /ligand="ATP"
BINDING 236 238 /ligand="substrate" H-D-T
ACT_SITE 237 237 /note="Proton acceptor" D
BINDING 83 83 /ligand="substrate" [GA]
BINDING 259 259 /ligand="ATP"
BINDING 296 296 /ligand="substrate" N
BINDING 304 304 /ligand="ATP"
BINDING 402 402 /ligand="ATP"
DISULFID 68 222 C-x*-C
DISULFID 353 370 C-x*-C
DISULFID 413 417 C-x*-C

Additional information [?]

Size range 467-496 amino acids
Related rules None
Fusion Nter: None Cter: MF_00541 (rhaA)

View rule in raw text format (no links)