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HAMAP rule MF_01545

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General rule information [?]

Accession MF_01545
Dates 4-NOV-2005 (Created)
19-NOV-2019 (Last updated, Version 23)
Name AaeB
Scope(s) Bacteria
Template(s) P46481 (AAEB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01545 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AAEB
Protein name RecName: Full=p-hydroxybenzoic acid efflux pump subunit AaeB;
                 Short=pHBA efflux pump protein B;
Gene name Name=aaeB;

Comments [?]

FUNCTIONForms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
case <OC:Escherichia>
INDUCTIONPositively coregulated with aaeA and aaeX by AaeR.
end case
SIMILARITYBelongs to the aromatic acid exporter ArAE (TC 2.A.85) family.

Keywords [?]

Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Transmembrane helix

Gene Ontology [?]

GO:0022857; Molecular function:transmembrane transporter activity
GO:0055085; Biological process:transmembrane transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF04632; FUSC; 1;
General Transmembrane; -; 11;

Features [?]

Additional information [?]

Size range 648-662 amino acids
Related rules None
Fusion Nter: None Cter: None

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