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Annotation rule MF_01559 |
General rule information
[?]
Accession |
MF_01559 |
Dates |
13-DEC-2005 (Created) 19-NOV-2019 (Last updated, Version 21) |
Scope |
Bacteria; Proteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=L-lactate dehydrogenase;
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EC 1.1.-.-;
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Function |
Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain. |
Catalytic activity |
RHEA:45816: (S)-lactate + A = AH2 + pyruvate
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Cofactor |
FMN |
case <OC:Pseudomonas>
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Peripheral membrane protein. |
end case
Similarity |
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0016614; Molecular function: oxidoreductase activity, acting on CH-OH group of donors.
GO:0019516; Biological process: lactate oxidation.
GO:0005886; Cellular component: plasma membrane.
From: LLDD_ECOLI (P33232) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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NP_BIND
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|
306
|
|
330
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FMN
|
|
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|
|
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ACT_SITE
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|
275
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275
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Proton acceptor
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H
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|
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BINDING
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|
24
|
|
24
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|
Substrate
|
|
|
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Y
|
|
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BINDING
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|
106
|
|
106
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|
FMN
|
|
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S
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|
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BINDING
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|
127
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|
127
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|
FMN
|
|
|
|
Q
|
|
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BINDING
|
|
129
|
|
129
|
|
Substrate
|
|
|
|
Y
|
|
|
BINDING
|
|
155
|
|
155
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|
FMN
|
|
|
|
T
|
|
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BINDING
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|
164
|
|
164
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|
Substrate
|
|
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R
|
|
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BINDING
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|
251
|
|
251
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|
FMN
|
|
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K
|
|
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BINDING
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278
|
|
278
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Substrate
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R
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Additional information
[?]
Size range |
378-401 amino acids |
Related rules |
None |
Fusion |
None |