Function |
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD. |
Catalytic activity |
RHEA:22364: L-quinate + NAD(+) = 3-dehydroquinate + H(+) + NADH
EC 1.1.1.282
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RHEA:18425: L-quinate + NADP(+) = 3-dehydroquinate + H(+) + NADPH
EC 1.1.1.282
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RHEA:17737: NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH
EC 1.1.1.282
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RHEA:17741: NAD(+) + shikimate = 3-dehydroshikimate + H(+) + NADH
EC 1.1.1.282
|
Pathway |
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. |
Subunit |
Homodimer. |
Similarity |
Belongs to the shikimate dehydrogenase family. |