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HAMAP rule MF_01585

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General rule information [?]

Accession MF_01585
Dates 10-OCT-2007 (Created)
19-NOV-2019 (Last updated, Version 16)
Name MFS_LplT
Scope(s) Bacteria
Enterobacterales
Template(s) P39196 (LPLT_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01585 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier LPLT
Protein name RecName: Full=Lysophospholipid transporter LplT;
Gene name Name=lplT;

Comments [?]

FUNCTIONCatalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.

Keywords [?]

Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Lipid transport
Membrane
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0005319; Molecular function:lipid transporter activity
GO:0006869; Biological process:lipid transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

PROSITE PS50850; MFS; 1;
Pfam PF07690; MFS_1; 1;
General Transmembrane; -; 11-12;

Features [?]

From: LPLT_ECOLI (P39196)
Key From To Description Tag Condition FTGroup
case <OC:Escherichia> or <OC:Shigella>
TOPO_DOM Nter 17 /note="Periplasmic"
TRANSMEM 18 38 /note="Helical"
TOPO_DOM 39 52 /note="Cytoplasmic"
TRANSMEM 53 73 /note="Helical"
TOPO_DOM 74 90 /note="Periplasmic"
TRANSMEM 91 111 /note="Helical"
TOPO_DOM 112 144 /note="Cytoplasmic"
TRANSMEM 145 165 /note="Helical"
TOPO_DOM 166 166 /note="Periplasmic"
TRANSMEM 167 187 /note="Helical"
TOPO_DOM 188 226 /note="Cytoplasmic"
TRANSMEM 227 247 /note="Helical"
TOPO_DOM 248 256 /note="Periplasmic"
TRANSMEM 257 277 /note="Helical"
TOPO_DOM 278 280 /note="Cytoplasmic"
TRANSMEM 281 301 /note="Helical"
TOPO_DOM 302 304 /note="Periplasmic"
TRANSMEM 305 325 /note="Helical"
TOPO_DOM 326 343 /note="Cytoplasmic"
TRANSMEM 344 364 /note="Helical"
TOPO_DOM 365 366 /note="Periplasmic"
TRANSMEM 367 387 /note="Helical"
TOPO_DOM 388 Cter /note="Cytoplasmic"
end case

Additional information [?]

Size range 396-407 amino acids
Related rules None
Fusion Nter: None Cter: None



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