HAMAP rule MF_01585
General rule information
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| Accession | MF_01585 |
| Dates | 10-OCT-2007 (Created) 19-NOV-2019 (Last updated, Version 16) |
| Name | MFS_LplT |
| Scope | Bacteria; Enterobacterales |
| Template | P39196 (LPLT_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell. |
case not defined <Property:Membrane> or <Property:Membrane=1>
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
| Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
end case
| Similarity | Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0005319; Molecular function: lipid transporter activity.
GO:0006869; Biological process: lipid transport.
GO:0005886; Cellular component: plasma membrane.
GO:0006869; Biological process: lipid transport.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Computed features
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case not <OC:Escherichia> and not <OC:Shigella>
| General | Transmembrane; -; 11-12; trigger=yes; |
end case
Features
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case <OC:Escherichia> or <OC:Shigella>
| From: LPLT_ECOLI (P39196) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 17 | Periplasmic | |||||||||
| TRANSMEM | 18 | 38 | Helical | |||||||||
| TOPO_DOM | 39 | 52 | Cytoplasmic | |||||||||
| TRANSMEM | 53 | 73 | Helical | |||||||||
| TOPO_DOM | 74 | 90 | Periplasmic | |||||||||
| TRANSMEM | 91 | 111 | Helical | |||||||||
| TOPO_DOM | 112 | 144 | Cytoplasmic | |||||||||
| TRANSMEM | 145 | 165 | Helical | |||||||||
| TOPO_DOM | 166 | 166 | Periplasmic | |||||||||
| TRANSMEM | 167 | 187 | Helical | |||||||||
| TOPO_DOM | 188 | 226 | Cytoplasmic | |||||||||
| TRANSMEM | 227 | 247 | Helical | |||||||||
| TOPO_DOM | 248 | 256 | Periplasmic | |||||||||
| TRANSMEM | 257 | 277 | Helical | |||||||||
| TOPO_DOM | 278 | 280 | Cytoplasmic | |||||||||
| TRANSMEM | 281 | 301 | Helical | |||||||||
| TOPO_DOM | 302 | 304 | Periplasmic | |||||||||
| TRANSMEM | 305 | 325 | Helical | |||||||||
| TOPO_DOM | 326 | 343 | Cytoplasmic | |||||||||
| TRANSMEM | 344 | 364 | Helical | |||||||||
| TOPO_DOM | 365 | 366 | Periplasmic | |||||||||
| TRANSMEM | 367 | 387 | Helical | |||||||||
| TOPO_DOM | 388 | Cter | Cytoplasmic | |||||||||
end case
Additional information
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| Size range | 396-407 amino acids |
| Related rules | None |
| Fusion | None |