HAMAP rule MF_01596
General rule information
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Accession | MF_01596 |
Dates | 20-MAR-2008 (Created)
19-NOV-2019 (Last updated, Version 11) |
Name | MgrB |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P64512 (MGRB_ECOLI); D0ZK39 (MGRB_SALT1); P0DM79 (MGRB_YERPE); [ Recover all ] |
Triggered by |
HAMAP; MF_01596 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | MGRB |
Protein name | RecName: Full=PhoP/PhoQ regulator MgrB; |
Gene name | Name=mgrB; |
Comments
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FUNCTION | PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. |
SUBUNIT | May form homooligomers. Probably interacts with the periplasmic domain of PhoQ. |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the MgrB family. |
Keywords
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Cell membrane | |
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Membrane | |
Transmembrane |
Gene Ontology
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GO:0070298; Biological process:negative regulation of phosphorelay signal transduction system |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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General | Transmembrane; -; 1; |
Features
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Additional information
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Size range | 46-50 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |