HAMAP rule MF_01596

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01596
Accession	MF_01596
Dates	20-MAR-2008 (Created) 19-NOV-2019 (Last updated, Version 12)
Name	MgrB
Scope(s)	Bacteria Enterobacterales
Template(s)	P64512; D0ZK39; P0DM79; [ Recover all ]
Triggered by	HAMAP; MF_01596 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MGRB
Protein name	RecName: Full=PhoP/PhoQ regulator MgrB;
Gene name	Name=mgrB;

Comments [?]

FUNCTION	PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
SUBUNIT	May form homooligomers. Probably interacts with the periplasmic domain of PhoQ.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Single-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Single-pass membrane protein.
end case
SIMILARITY	Belongs to the MgrB family.

Keywords [?]

Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Membrane
Transmembrane

Gene Ontology [?]

GO:0070298; Biological process:negative regulation of phosphorelay signal transduction system

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

General

Features [?]

Additional information [?]