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HAMAP rule MF_01596

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General rule information [?]

Accession MF_01596
Dates 20-MAR-2008 (Created)
19-NOV-2019 (Last updated, Version 11)
Name MgrB
Bacteria; Enterobacterales
Templates P64512 (MGRB_ECOLI); D0ZK39 (MGRB_SALT1); P0DM79 (MGRB_YERPE): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=PhoP/PhoQ regulator MgrB;
Gene name

Comments [?]

Function PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
Subunit May form homooligomers. Probably interacts with the periplasmic domain of PhoQ.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Single-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Single-pass membrane protein.
end case
Similarity Belongs to the MgrB family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0070298; Biological process: negative regulation of phosphorelay signal transduction system.
GO:0005886; Cellular component: plasma membrane.

Computed features [?]

General Transmembrane; -; 1; trigger=yes;

Additional information [?]

Size range 46-50 amino acids
Related rules None
Fusion None