HAMAP rule MF_01599

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01599
Accession	MF_01599
Dates	10-APR-2008 (Created) 03-SEP-2024 (Last updated, Version 17)
Name	NhaB
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P0AFA7; Q9I2S5; Q56577; Q87N04; [ Recover all ]
Triggered by	HAMAP; MF_01599 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	NHAB
Protein name	RecName: Full=Na(+)/H(+) antiporter NhaB; AltName: Full=Sodium/proton antiporter NhaB;
Gene name	Name=nhaB;

Comments [?]

FUNCTION	Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
CATALYTIC ACTIVITY	Reaction=2 Na(+)(in) + 3 H(+)(out) = 2 Na(+)(out) + 3 H(+)(in); Xref=Rhea:RHEA:29247, ChEBI:CHEBI:15378, ChEBI:CHEBI:29101; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29248;
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
end case
SIMILARITY	Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

Keywords [?]

Antiport
Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Ion transport
Membrane
Sodium
Sodium transport
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0015297; Molecular function:antiporter activity

GO:0015081; Molecular function:sodium ion transmembrane transporter activity

GO:0006814; Biological process:sodium ion transport

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]