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HAMAP rule MF_01599

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General rule information [?]

Accession MF_01599
Dates 10-APR-2008 (Created)
1-JUN-2023 (Last updated, Version 15)
Name NhaB
Scope(s) Bacteria
Template(s) P0AFA7 (NHAB_ECOLI); Q9I2S5 (NHAB_PSEAE); Q56577 (NHAB_VIBAL); Q87N04 (NHAB_VIBPA); [ Recover all ]
Triggered by HAMAP; MF_01599 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NHAB
Protein name RecName: Full=Na(+)/H(+) antiporter NhaB;
AltName: Full=Sodium/proton antiporter NhaB;
Gene name Name=nhaB;

Comments [?]

FUNCTIONNa(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
CATALYTIC ACTIVITY Reaction=3 H(+)(out) + 2 Na(+)(in) = 3 H(+)(in) + 2 Na(+)(out); Xref=Rhea:RHEA:29247, ChEBI:CHEBI:15378, ChEBI:CHEBI:29101; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29248;
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

Keywords [?]

Gene Ontology [?]

GO:0015297; Molecular function:antiporter activity
GO:0015081; Molecular function:sodium ion transmembrane transporter activity
GO:0006814; Biological process:sodium ion transport
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF06450; NhaB; 1;
NCBIfam TIGR00774; NhaB; 1;
General Transmembrane; -; 10-13;

Features [?]

Additional information [?]

Size range 499-533 amino acids
Related rules None
Fusion Nter: None Cter: None

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