HAMAP rule MF_01599
General rule information
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Accession | MF_01599 |
Dates | 10-APR-2008 (Created)
1-JUN-2023 (Last updated, Version 15) |
Name | NhaB |
Scope(s) |
Bacteria Gammaproteobacteria |
Template(s) | P0AFA7 (NHAB_ECOLI); Q9I2S5 (NHAB_PSEAE); Q56577 (NHAB_VIBAL); Q87N04 (NHAB_VIBPA); [ Recover all ] |
Triggered by |
HAMAP; MF_01599 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NHAB |
Protein name | RecName: Full=Na(+)/H(+) antiporter NhaB; AltName: Full=Sodium/proton antiporter NhaB; |
Gene name | Name=nhaB; |
Comments
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FUNCTION | Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. |
CATALYTIC ACTIVITY | Reaction=3 H(+)(out) + 2 Na(+)(in) = 3 H(+)(in) + 2 Na(+)(out); Xref=Rhea:RHEA:29247, ChEBI:CHEBI:15378, ChEBI:CHEBI:29101; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29248; |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
end case | |
SIMILARITY | Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family. |
Keywords
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Antiport | |
Cell membrane | |
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Ion transport | |
Membrane | |
Sodium | |
Sodium transport | |
Transmembrane | |
Transport | |
Transmembrane helix |
Gene Ontology
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GO:0015297; Molecular function:antiporter activity |
GO:0015081; Molecular function:sodium ion transmembrane transporter activity |
GO:0006814; Biological process:sodium ion transport |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF06450; NhaB; 1; |
PRINTS | PR00173; EDTRNSPORT; 1; |
NCBIfam | TIGR00774; NhaB; 1; |
General | Transmembrane; -; 10-13; |
Features
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Additional information
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Size range | 499-533 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |