HAMAP rule MF_01604
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01604 |
| Accession | MF_01604 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 17) |
| Name | Thiamine_kinase |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P75948; [ Recover all ] |
| Triggered by |
HAMAP; MF_01604 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | THIK |
| Protein name | RecName: Full=Thiamine kinase; EC=2.7.1.89; |
| Gene name | Name=thiK; |
Comments
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| FUNCTION | Catalyzes the phosphorylation of thiamine to thiamine phosphate. |
| CATALYTIC ACTIVITY | Reaction=thiamine + ATP = thiamine phosphate + ADP + H(+); Xref=Rhea:RHEA:12012, ChEBI:CHEBI:15378, ChEBI:CHEBI:18385, ChEBI:CHEBI:30616, ChEBI:CHEBI:37575, ChEBI:CHEBI:456216; EC=2.7.1.89; |
| PATHWAY | Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from thiamine: step 1/1. |
| SIMILARITY | Belongs to the thiamine kinase family. |
Keywords
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Gene Ontology
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| GO:0019165; Molecular function:thiamine kinase activity |
| GO:0016310; Biological process:phosphorylation |
| GO:0009229; Biological process:thiamine diphosphate biosynthetic process |
Cross-references
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Features
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Additional information
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| Size range | 274-274 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |