HAMAP rule MF_01604

General rule information [?]

Accession	MF_01604
Dates	12-FEB-2005 (Created) 1-MAR-2024 (Last updated, Version 15)
Name	Thiamine_kinase
Scope(s)	Bacteria Enterobacterales
Template(s)	P75948 (THIK_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01604 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	THIK
Protein name	RecName: Full=Thiamine kinase; EC=2.7.1.89;
Gene name	Name=thiK;

Comments [?]

FUNCTION	Catalyzes the phosphorylation of thiamine to thiamine phosphate.
CATALYTIC ACTIVITY	Reaction=ATP + thiamine = ADP + H(+) + thiamine phosphate; Xref=Rhea:RHEA:12012, ChEBI:CHEBI:15378, ChEBI:CHEBI:18385, ChEBI:CHEBI:30616, ChEBI:CHEBI:37575, ChEBI:CHEBI:456216; EC=2.7.1.89;
PATHWAY	Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from thiamine: step 1/1.
SIMILARITY	Belongs to the thiamine kinase family.

Keywords [?]

Gene Ontology [?]

GO:0019165; Molecular function:thiamine kinase activity

GO:0016310; Biological process:phosphorylation

GO:0009229; Biological process:thiamine diphosphate biosynthetic process

Cross-references [?]

Pfam	PF01636; APH; 1;
NCBIfam	TIGR02721; ycfN_thiK; 1;

Features [?]

Additional information [?]