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HAMAP rule MF_01604

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General rule information [?]

Accession MF_01604
Dates 12-FEB-2005 (Created)
1-MAR-2024 (Last updated, Version 15)
Name Thiamine_kinase
Scope(s) Bacteria
Template(s) P75948 (THIK_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01604 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier THIK
Protein name RecName: Full=Thiamine kinase;
Gene name Name=thiK;

Comments [?]

FUNCTIONCatalyzes the phosphorylation of thiamine to thiamine phosphate.
CATALYTIC ACTIVITY Reaction=ATP + thiamine = ADP + H(+) + thiamine phosphate; Xref=Rhea:RHEA:12012, ChEBI:CHEBI:15378, ChEBI:CHEBI:18385, ChEBI:CHEBI:30616, ChEBI:CHEBI:37575, ChEBI:CHEBI:456216; EC=;
PATHWAYCofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from thiamine: step 1/1.
SIMILARITYBelongs to the thiamine kinase family.

Keywords [?]

Gene Ontology [?]

GO:0019165; Molecular function:thiamine kinase activity
GO:0016310; Biological process:phosphorylation
GO:0009229; Biological process:thiamine diphosphate biosynthetic process

Cross-references [?]

Pfam PF01636; APH; 1;
NCBIfam TIGR02721; ycfN_thiK; 1;

Features [?]

Additional information [?]

Size range 274-274 amino acids
Related rules None
Fusion Nter: None Cter: None

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