HAMAP rule MF_01604
General rule information
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Accession | MF_01604 |
Dates | 12-FEB-2005 (Created)
1-MAR-2024 (Last updated, Version 15) |
Name | Thiamine_kinase |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P75948 (THIK_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01604 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | THIK |
Protein name | RecName: Full=Thiamine kinase; EC=2.7.1.89; |
Gene name | Name=thiK; |
Comments
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FUNCTION | Catalyzes the phosphorylation of thiamine to thiamine phosphate. |
CATALYTIC ACTIVITY | Reaction=ATP + thiamine = ADP + H(+) + thiamine phosphate; Xref=Rhea:RHEA:12012, ChEBI:CHEBI:15378, ChEBI:CHEBI:18385, ChEBI:CHEBI:30616, ChEBI:CHEBI:37575, ChEBI:CHEBI:456216; EC=2.7.1.89; |
PATHWAY | Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from thiamine: step 1/1. |
SIMILARITY | Belongs to the thiamine kinase family. |
Keywords
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Gene Ontology
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GO:0019165; Molecular function:thiamine kinase activity |
GO:0016310; Biological process:phosphorylation |
GO:0009229; Biological process:thiamine diphosphate biosynthetic process |
Cross-references
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Features
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Additional information
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Size range | 274-274 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |