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HAMAP rule MF_01605

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General rule information [?]

Accession MF_01605
Dates 14-FEB-2005 (Created)
25-JAN-2024 (Last updated, Version 16)
Name 6P_gluconolactonase
Scope(s) Bacteria
Template(s) P52697 (6PGL_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01605 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier 6PGL
Protein name RecName: Full=6-phosphogluconolactonase;
Gene name Name=pgl;

Comments [?]

FUNCTIONCatalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
CATALYTIC ACTIVITY Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=;
PATHWAYCarbohydrate degradation; pentose phosphate pathway; D- ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
SIMILARITYBelongs to the cycloisomerase 2 family.

Keywords [?]

Gene Ontology [?]

GO:0017057; Molecular function:6-phosphogluconolactonase activity
GO:0009051; Biological process:pentose-phosphate shunt, oxidative branch

Cross-references [?]

Features [?]

From: 6PGL_ECOLI (P52697)
Key From To Description Tag Condition FTGroup
case <OC:Escherichia> or <OC:Shigella>
MOD_RES 287 287 /note="N6-acetyllysine" K
end case

Additional information [?]

Size range 328-338 amino acids
Related rules None
Fusion Nter: None Cter: None

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