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HAMAP rule MF_01616

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General rule information [?]

Accession MF_01616
Dates 5-JUL-2005 (Created)
19-NOV-2019 (Last updated, Version 24)
Name MltC
Scope
Bacteria; Gammaproteobacteria
Template P0C066 (MLTC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MLTC
Protein name
RecName: Full=Membrane-bound lytic murein transglycosylase C;
EC 4.2.2.n1;
AltName: Full=Murein lyase C;
Flags: Precursor;
Gene name
mltC

Comments [?]

Function Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
Catalytic activity Reaction=Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.; EC=4.2.2.n1;
case <Feature:PS51257>
Subcellular location Cell outer membrane; Lipid-anchor.
end case
Similarity Belongs to the transglycosylase Slt family.

Keywords [?]

case <Feature:PS51257>
end case

Gene Ontology [?]

GO:0008933; Molecular function: lytic transglycosylase activity.
GO:0016998; Biological process: cell wall macromolecule catabolic process.
case <Feature:PS51257>
GO:0009279; Cellular component: cell outer membrane.
end case

Cross-references [?]

PROSITE PS51257; PROKAR_LIPOPROTEIN; 1; trigger=PRU00303;
PS00922; TRANSGLYCOSYLASE; 1;
Pfam PF01464; SLT; 1;

Additional information [?]

Size range 357-367 amino acids
Related rules None
Fusion None