HAMAP rule MF_01616
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01616 |
| Accession | MF_01616 |
| Dates | 05-JUL-2005 (Created)
20-MAR-2025 (Last updated, Version 26) |
| Name | MltC |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P0C066; [ Recover all ] |
| Triggered by |
HAMAP; MF_01616 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MLTC |
| Protein name | RecName: Full=Membrane-bound lytic murein transglycosylase C; EC=4.2.2.n1; AltName: Full=Murein lyase C; Flags: Precursor; |
| Gene name | Name=mltC; |
Comments
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| FUNCTION | Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. |
| CATALYTIC ACTIVITY | Reaction=Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.; EC=4.2.2.n1; |
| case <Feature:PS51257> | |
| SUBCELLULAR LOCATION | Cell outer membrane; Lipid-anchor. |
| end case | |
| SIMILARITY | Belongs to the transglycosylase Slt family. |
Keywords
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| Cell outer membrane | |
| Cell wall biogenesis/degradation | |
| Lyase | |
| Membrane | |
| Signal | |
| case <Feature:PS51257> | |
| Lipoprotein | |
| Palmitate | |
| end case | |
Gene Ontology
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| GO:0008933; Molecular function:peptidoglycan lytic transglycosylase activity | |
| GO:0016998; Biological process:cell wall macromolecule catabolic process | |
| case <Feature:PS51257> | |
| GO:0009279; Cellular component:cell outer membrane | |
| end case | |
Cross-references
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Features
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Additional information
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| Size range | 357-367 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |