HAMAP rule MF_01628

General rule information [?]

Accession	MF_01628
Dates	14-DEC-2005 (Created) 26-JAN-2023 (Last updated, Version 16)

Name	Thymid_phosp

Scope

Bacteria; Pseudomonadota

Template

P07650 (TYPH_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

TYPH

Protein name

RecName:		Full=Thymidine phosphorylase;
		EC 2.4.2.4;
AltName:		Full=TdRPase;

Gene name

deoA

Comments [?]

Function	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
Catalytic activity	RHEA:16037: phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine EC 2.4.2.4
Pathway	Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
Subunit	Homodimer.
Similarity	Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.

Keywords [?]

Gene Ontology [?]

GO:0009032; Molecular function: thymidine phosphorylase activity.
GO:0046104; Biological process: thymidine metabolic process.

Cross-references [?]

Additional information [?]