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Annotation rule MF_01628
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General rule information [?]

Accession MF_01628
Dates 14-DEC-2005 (Created)
19-NOV-2019 (Last updated, Version 15)
Name Thymid_phosp
Scope
Bacteria; Proteobacteria
Template P07650 (TYPH_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TYPH
Protein name
RecName: Full=Thymidine phosphorylase;
EC 2.4.2.4;
AltName: Full=TdRPase;
Gene name
deoA

Comments [?]

Function The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
Catalytic activity RHEA:16037: phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine
EC 2.4.2.4
Pathway Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
Subunit Homodimer.
Similarity Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.

Keywords [?]


Gene Ontology [?]

GO:0009032; Molecular function: thymidine phosphorylase activity.
GO:0046104; Biological process: thymidine metabolic process.

Cross-references [?]

PROSITE PS00647; THYMID_PHOSPHORYLASE; 1;
Pfam PF02885; Glycos_trans_3N; 1;
PF00591; Glycos_transf_3; 1;
TIGRFAMs TIGR02643; T_phosphoryl; 1;

Additional information [?]

Size range 438-448 amino acids
Related rules None
Fusion None