HAMAP rule MF_01628
General rule information
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Accession |
MF_01628 |
Dates |
14-DEC-2005 (Created) 26-JAN-2023 (Last updated, Version 16) |
Scope |
Bacteria; Pseudomonadota |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Thymidine phosphorylase;
|
|
EC 2.4.2.4;
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AltName:
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Full=TdRPase;
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|
Function |
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. |
Catalytic activity |
RHEA:16037: phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine
EC 2.4.2.4
|
Pathway |
Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2. |
Subunit |
Homodimer. |
Similarity |
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. |
GO:0009032; Molecular function: thymidine phosphorylase activity.
GO:0046104; Biological process: thymidine metabolic process.
Additional information
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Size range |
438-448 amino acids |
Related rules |
None |
Fusion |
None |