HAMAP rule MF_01632
General rule information
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| Accession | MF_01632 |
| Dates | 6-JUN-2006 (Created) 26-JAN-2023 (Last updated, Version 26) |
| Name | UbiC |
| Scope | Bacteria; Pseudomonadota |
| Template | P26602 (UBIC_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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case <OC:Enterobacterales>
| Protein name |
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else
| Protein name |
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end case
| Gene name |
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Comments
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| Function | Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. |
| Catalytic activity | RHEA:16505: chorismate = 4-hydroxybenzoate + pyruvate
EC 4.1.3.40 |
| Pathway | Cofactor biosynthesis; ubiquinone biosynthesis. |
case <OC:Enterobacterales>
| Subunit | Monomer. |
end case
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the UbiC family. |
Keywords
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Gene Ontology
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GO:0008813; Molecular function: chorismate lyase activity.
GO:0006744; Biological process: ubiquinone biosynthetic process.
GO:0042866; Biological process: pyruvate biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0006744; Biological process: ubiquinone biosynthetic process.
GO:0042866; Biological process: pyruvate biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF04345; Chor_lyase; 1; |
Features
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| From: UBIC_ECOLI (P26602) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 35 | 35 | /ligand="substrate | M | ||||||||
| BINDING | 77 | 77 | /ligand="substrate | R | ||||||||
| BINDING | 115 | 115 | /ligand="substrate | [LI] | ||||||||
| BINDING | 156 | 156 | /ligand="substrate | E | ||||||||
Additional information
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| Size range | 162-227 amino acids |
| Related rules | None |
| Fusion | None |