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HAMAP rule MF_01632

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General rule information [?]

Accession MF_01632
Dates 6-JUN-2006 (Created)
26-JAN-2023 (Last updated, Version 26)
Name UbiC
Scope(s) Bacteria
Template(s) P26602 (UBIC_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01632 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier UBIC
case <OC:Enterobacterales>
Protein name RecName: Full=Chorismate pyruvate-lyase;
Protein name RecName: Full=Probable chorismate pyruvate-lyase;
end case
Gene name Name=ubiC;

Comments [?]

FUNCTIONRemoves the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
CATALYTIC ACTIVITY Reaction=chorismate = 4-hydroxybenzoate + pyruvate; Xref=Rhea:RHEA:16505, ChEBI:CHEBI:15361, ChEBI:CHEBI:17879, ChEBI:CHEBI:29748; EC=;
PATHWAYCofactor biosynthesis; ubiquinone biosynthesis.
case <OC:Enterobacterales>
end case
SIMILARITYBelongs to the UbiC family.

Keywords [?]

Gene Ontology [?]

GO:0008813; Molecular function:chorismate lyase activity
GO:0006744; Biological process:ubiquinone biosynthetic process
GO:0042866; Biological process:pyruvate biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF04345; Chor_lyase; 1;

Features [?]

From: UBIC_ECOLI (P26602)
Key From To Description Tag Condition FTGroup
BINDING 35 35 /ligand="substrate" M
BINDING 77 77 /ligand="substrate" R
BINDING 115 115 /ligand="substrate" [LI]
BINDING 156 156 /ligand="substrate" E

Additional information [?]

Size range 162-227 amino acids
Related rules None
Fusion Nter: None Cter: None

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