HAMAP rule MF_01632
General rule information
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Accession | MF_01632 |
Dates | 6-JUN-2006 (Created)
26-JAN-2023 (Last updated, Version 26) |
Name | UbiC |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P26602 (UBIC_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01632 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | UBIC |
case <OC:Enterobacterales> | |
Protein name | RecName: Full=Chorismate pyruvate-lyase; Short=CL; Short=CPL; EC=4.1.3.40; |
else | |
Protein name | RecName: Full=Probable chorismate pyruvate-lyase; Short=CL; Short=CPL; EC=4.1.3.40; |
end case | |
Gene name | Name=ubiC; |
Comments
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FUNCTION | Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. |
CATALYTIC ACTIVITY | Reaction=chorismate = 4-hydroxybenzoate + pyruvate; Xref=Rhea:RHEA:16505, ChEBI:CHEBI:15361, ChEBI:CHEBI:17879, ChEBI:CHEBI:29748; EC=4.1.3.40; |
PATHWAY | Cofactor biosynthesis; ubiquinone biosynthesis. |
case <OC:Enterobacterales> | |
SUBUNIT | Monomer. |
end case | |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the UbiC family. |
Keywords
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Gene Ontology
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GO:0008813; Molecular function:chorismate lyase activity |
GO:0006744; Biological process:ubiquinone biosynthetic process |
GO:0042866; Biological process:pyruvate biosynthetic process |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Pfam | PF04345; Chor_lyase; 1; |
Features
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From: UBIC_ECOLI (P26602) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 35 | 35 | /ligand="substrate" | M | ||||||||
BINDING | 77 | 77 | /ligand="substrate" | R | ||||||||
BINDING | 115 | 115 | /ligand="substrate" | [LI] | ||||||||
BINDING | 156 | 156 | /ligand="substrate" | E |
Additional information
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Size range | 162-227 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |