HAMAP rule MF_01632

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01632
Accession	MF_01632
Dates	06-JUN-2006 (Created) 26-JAN-2023 (Last updated, Version 27)
Name	UbiC
Scope(s)	Bacteria Pseudomonadota
Template(s)	P26602; [ Recover all ]
Triggered by	HAMAP; MF_01632 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	UBIC
case <OC:Enterobacterales>
Protein name	RecName: Full=Chorismate pyruvate-lyase; Short=CL; Short=CPL; EC=4.1.3.40;
else
Protein name	RecName: Full=Probable chorismate pyruvate-lyase; Short=CL; Short=CPL; EC=4.1.3.40;
end case
Gene name	Name=ubiC;

Comments [?]

FUNCTION	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
CATALYTIC ACTIVITY	Reaction=chorismate = 4-hydroxybenzoate + pyruvate; Xref=Rhea:RHEA:16505, ChEBI:CHEBI:15361, ChEBI:CHEBI:17879, ChEBI:CHEBI:29748; EC=4.1.3.40;
PATHWAY	Cofactor biosynthesis; ubiquinone biosynthesis.
case <OC:Enterobacterales>
SUBUNIT	Monomer.
end case
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the UbiC family.

Keywords [?]

Gene Ontology [?]

GO:0008813; Molecular function:chorismate lyase activity

GO:0006744; Biological process:ubiquinone biosynthetic process

GO:0042866; Biological process:pyruvate biosynthetic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF04345; Chor_lyase; 1;

Features [?]

From: UBIC_ECOLI (P26602)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="substrate"

BINDING

/ligand="substrate"

BINDING

115

/ligand="substrate"

[LI]

BINDING

156

/ligand="substrate"

Additional information [?]