HAMAP rule MF_01637
General rule information
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| Accession | MF_01637 |
| Dates | 22-NOV-2006 (Created)
19-NOV-2022 (Last updated, Version 13) |
| Name | Fe_S_biogen_NfuA |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P63020 (NFUA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01637 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NFUA |
| Protein name | RecName: Full=Fe/S biogenesis protein NfuA; |
| Gene name | Name=nfuA; |
Comments
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| FUNCTION | Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. |
| COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.; |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the NfuA family. |
Keywords
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Gene Ontology
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| GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding |
| GO:0016226; Biological process:iron-sulfur cluster assembly |
| GO:0051604; Biological process:protein maturation |
Cross-references
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Features
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| From: NFUA_ECOLI (P63020) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 149 | 149 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | ||||||||
| BINDING | 152 | 152 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | ||||||||
Additional information
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| Size range | 184-212 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |