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HAMAP rule MF_01637

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General rule information [?]

Accession MF_01637
Dates 22-NOV-2006 (Created)
19-NOV-2022 (Last updated, Version 13)
Name Fe_S_biogen_NfuA
Scope(s) Bacteria
Template(s) P63020 (NFUA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01637 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NFUA
Protein name RecName: Full=Fe/S biogenesis protein NfuA;
Gene name Name=nfuA;

Comments [?]

FUNCTIONInvolved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
COFACTOR Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Note=Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.;
SIMILARITYBelongs to the NfuA family.

Keywords [?]

Gene Ontology [?]

GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding
GO:0016226; Biological process:iron-sulfur cluster assembly
GO:0051604; Biological process:protein maturation

Cross-references [?]

Pfam PF01521; Fe-S_biosyn; 1;
Pfam PF01106; NifU; 1;

Features [?]

From: NFUA_ECOLI (P63020)
Key From To Description Tag Condition FTGroup
BINDING 149 149 /ligand="[4Fe-4S] cluster"
BINDING 152 152 /ligand="[4Fe-4S] cluster"

Additional information [?]

Size range 184-212 amino acids
Related rules None
Fusion Nter: None Cter: None

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