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HAMAP rule MF_01637

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General rule information [?]

Accession MF_01637
Dates 22-NOV-2006 (Created)
19-NOV-2022 (Last updated, Version 13)
Name Fe_S_biogen_NfuA
Bacteria; Gammaproteobacteria
Template P63020 (NFUA_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Fe/S biogenesis protein NfuA;
Gene name

Comments [?]

Function Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
Subunit Homodimer.
Similarity Belongs to the NfuA family.

Keywords [?]

Gene Ontology [?]

GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0016226; Biological process: iron-sulfur cluster assembly.
GO:0051604; Biological process: protein maturation.

Cross-references [?]

Pfam PF01521; Fe-S_biosyn; 1;
PF01106; NifU; 1;

Features [?]

From: NFUA_ECOLI (P63020)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     149     149       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883     C  
BINDING     152     152       /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883     C  

Additional information [?]

Size range 184-212 amino acids
Related rules None
Fusion None