HAMAP rule MF_01637
General rule information
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| Accession | MF_01637 |
| Dates | 22-NOV-2006 (Created) 19-NOV-2022 (Last updated, Version 13) |
| Name | Fe_S_biogen_NfuA |
| Scope | Bacteria; Gammaproteobacteria |
| Template | P63020 (NFUA_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. |
| Cofactor | [4Fe-4S] cluster Note: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers. |
| Subunit | Homodimer. |
| Similarity | Belongs to the NfuA family. |
Keywords
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Gene Ontology
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GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding.
GO:0016226; Biological process: iron-sulfur cluster assembly.
GO:0051604; Biological process: protein maturation.
GO:0016226; Biological process: iron-sulfur cluster assembly.
GO:0051604; Biological process: protein maturation.
Cross-references
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Features
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| From: NFUA_ECOLI (P63020) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 149 | 149 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | ||||||||
| BINDING | 152 | 152 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883 | C | ||||||||
Additional information
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| Size range | 184-212 amino acids |
| Related rules | None |
| Fusion | None |