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Annotation rule MF_01639
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General rule information [?]

Accession MF_01639
Dates 29-NOV-2006 (Created)
19-NOV-2019 (Last updated, Version 18)
Name PdxY
Scope
Bacteria; Actinobacteria
Bacteria; Deinococci
Bacteria; Proteobacteria
Template P77150 (PDXY_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PDXY
Protein name
RecName: Full=Pyridoxal kinase PdxY;
Short=PL kinase;
EC 2.7.1.35;
Gene name
pdxY

Comments [?]

Function Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
Catalytic activity RHEA:10224: ATP + pyridoxal = ADP + H(+) + pyridoxal 5'-phosphate
EC 2.7.1.35
Cofactor Mg(2+)
Pathway Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxal: step 1/1.
Subunit Homodimer.
Similarity Belongs to the pyridoxine kinase family. PdxY subfamily.

Keywords [?]


Gene Ontology [?]

GO:0000287; Molecular function: magnesium ion binding.
GO:0005524; Molecular function: ATP binding.
GO:0008478; Molecular function: pyridoxal kinase activity.
GO:0009443; Biological process: pyridoxal 5'-phosphate salvage.

Cross-references [?]

Pfam PF08543; Phos_pyr_kin; 1;
TIGRFAMs TIGR00687; pyridox_kin; 1;

Features [?]

From: PDXY_ECOLI (P77150)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     209     212       ATP     R-x-x-[VLI]  
REGION (Optional)     45     46       Substrate binding     [TM]-Q  
BINDING     10     10       Substrate     S  
BINDING     112     112       ATP     D  
BINDING (Optional)     144     144       ATP; via carbonyl oxygen     [AV]  
BINDING     149     149       ATP     E  
BINDING (Optional)     182     182       ATP     K  
BINDING     224     224       Substrate     D  

Additional information [?]

Size range 283-299 amino acids
Related rules None
Fusion None
Comments SALTI contains a C-terminal deletion removing the last 68 aa, and may therefore be non-functional. This sequence is not shown in alignment and was not taken into account for the size range field.