HAMAP rule MF_01649
General rule information
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Accession | MF_01649 |
Dates | 17-APR-2008 (Created) 20-JUL-2020 (Last updated, Version 17) |
Name | HcaF |
Scope | Bacteria; Enterobacterales |
Template | Q47140 (HCAF_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively. |
Catalytic activity | RHEA:20357: 3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)
EC 1.14.12.19 |
RHEA:25058: (E)-cinnamate + H(+) + NADH + O2 = (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)
EC 1.14.12.19 |
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Pathway | Aromatic compound metabolism; 3-phenylpropanoate degradation. |
Subunit | This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD). |
Similarity | Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. |
Keywords
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Gene Ontology
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GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.
GO:0019439; Biological process: aromatic compound catabolic process.
Cross-references
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Pfam | PF00866; Ring_hydroxyl_B; 1; |
Additional information
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Size range | 172-180 amino acids |
Related rules | None |
Fusion | None |