HAMAP rule MF_01649

General rule information [?]

Accession	MF_01649
Dates	17-APR-2008 (Created) 20-JUL-2020 (Last updated, Version 17)

Name

HcaF

Scope

Bacteria; Enterobacterales

Template

Q47140 (HCAF_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

HCAF

Protein name

RecName:		Full=3-phenylpropionate/cinnamic acid dioxygenase subunit beta;
		EC 1.14.12.19;

Gene name

hcaF

Comments [?]

Function	Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
Catalytic activity	RHEA:20357: 3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+) EC 1.14.12.19
	RHEA:25058: (E)-cinnamate + H(+) + NADH + O2 = (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+) EC 1.14.12.19
Pathway	Aromatic compound metabolism; 3-phenylpropanoate degradation.
Subunit	This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).
Similarity	Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Keywords [?]

Gene Ontology [?]

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam	PF00866; Ring_hydroxyl_B; 1;

Additional information [?]