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Annotation rule MF_01649
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General rule information [?]

Accession MF_01649
Dates 17-APR-2008 (Created)
20-JUL-2020 (Last updated, Version 17)
Name HcaF
Scope
Bacteria; Enterobacterales
Template Q47140 (HCAF_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HCAF
Protein name
RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase subunit beta;
EC 1.14.12.19;
Gene name
hcaF

Comments [?]

Function Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
Catalytic activity RHEA:20357: 3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)
EC 1.14.12.19
RHEA:25058: (E)-cinnamate + H(+) + NADH + O2 = (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)
EC 1.14.12.19
Pathway Aromatic compound metabolism; 3-phenylpropanoate degradation.
Subunit This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).
Similarity Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Keywords [?]

Aromatic hydrocarbons catabolism
Dioxygenase
NAD
Oxidoreductase

Gene Ontology [?]

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam PF00866; Ring_hydroxyl_B; 1;

Additional information [?]

Size range 172-180 amino acids
Related rules None
Fusion None


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