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HAMAP rule MF_01649

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General rule information [?]

Accession MF_01649
Dates 17-APR-2008 (Created)
20-JUL-2020 (Last updated, Version 17)
Name HcaF
Scope(s) Bacteria
Template(s) Q47140 (HCAF_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01649 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HCAF
Protein name RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase subunit beta;
Gene name Name=hcaF;

Comments [?]

FUNCTIONPart of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
CATALYTIC ACTIVITY Reaction=3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6- dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+); Xref=Rhea:RHEA:20357, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:51057, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:60087; EC=;
CATALYTIC ACTIVITY Reaction=(E)-cinnamate + H(+) + NADH + O2 = (2E)-3-(cis-5,6- dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+); Xref=Rhea:RHEA:25058, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:15669, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:61451; EC=;
PATHWAYAromatic compound metabolism; 3-phenylpropanoate degradation.
SUBUNITThis dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).
SIMILARITYBelongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Keywords [?]

Gene Ontology [?]

GO:0008695; Molecular function:3-phenylpropionate dioxygenase activity
GO:0019439; Biological process:aromatic compound catabolic process

Cross-references [?]

Pfam PF00866; Ring_hydroxyl_B; 1;

Features [?]

Additional information [?]

Size range 172-180 amino acids
Related rules None
Fusion Nter: None Cter: None

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