HAMAP rule MF_01649

General rule information [?]

Accession	MF_01649
Dates	17-APR-2008 (Created) 12-MAR-2024 (Last updated, Version 18)
Name	HcaF
Scope(s)	Bacteria Enterobacterales
Template(s)	Q47140 (HCAF_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01649 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	HCAF
Protein name	RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase subunit beta; EC=1.14.12.19;
Gene name	Name=hcaF;

Comments [?]

FUNCTION	Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively.
CATALYTIC ACTIVITY	Reaction=3-phenylpropanoate + H(+) + NADH + O2 = 3-(cis-5,6- dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+); Xref=Rhea:RHEA:20357, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:51057, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:60087; EC=1.14.12.19;
CATALYTIC ACTIVITY	Reaction=(E)-cinnamate + H(+) + NADH + O2 = (2E)-3-(cis-5,6- dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+); Xref=Rhea:RHEA:25058, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:15669, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:61451; EC=1.14.12.19;
PATHWAY	Aromatic compound metabolism; 3-phenylpropanoate degradation.
SUBUNIT	This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD).
SIMILARITY	Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Keywords [?]

Gene Ontology [?]

GO:0008695; Molecular function:3-phenylpropionate dioxygenase activity

GO:0019380; Biological process:3-phenylpropionate catabolic process

Cross-references [?]

Pfam	PF00866; Ring_hydroxyl_B; 1;

Features [?]

Additional information [?]