HAMAP rule MF_01650
General rule information
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| Accession | MF_01650 |
| Dates | 17-APR-2008 (Created)
19-NOV-2022 (Last updated, Version 18) |
| Name | HcaC |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P0ABW0 (HCAC_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01650 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HCAC |
| Protein name | RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit; |
| Gene name | Name=hcaC; |
Comments
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| FUNCTION | Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. This protein seems to be a 2Fe-2S ferredoxin. |
| COFACTOR | Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135; Note=Binds 1 [2Fe-2S] cluster per subunit. |
| PATHWAY | Aromatic compound metabolism; 3-phenylpropanoate degradation. |
| SUBUNIT | This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (HcaE and HcaF), a ferredoxin (HcaC) and a ferredoxin reductase (HcaD). |
| SIMILARITY | Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family. |
Keywords
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Gene Ontology
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| GO:0008695; Molecular function:3-phenylpropionate dioxygenase activity |
| GO:0019439; Biological process:aromatic compound catabolic process |
Cross-references
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Features
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| From: HCAC_ECOLI (P0ABW0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 42 | 42 | /ligand="[2Fe-2S] cluster" /ligand_id="ChEBI:CHEBI:190135" |
C | ||||||||
| BINDING | 44 | 44 | /ligand="[2Fe-2S] cluster" /ligand_id="ChEBI:CHEBI:190135" |
H | ||||||||
| BINDING | 62 | 62 | /ligand="[2Fe-2S] cluster" /ligand_id="ChEBI:CHEBI:190135" |
C | ||||||||
| BINDING | 65 | 65 | /ligand="[2Fe-2S] cluster" /ligand_id="ChEBI:CHEBI:190135" |
H | ||||||||
Additional information
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| Size range | 105-106 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |