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HAMAP rule MF_01655

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General rule information [?]

Accession MF_01655
Dates 30-APR-2008 (Created)
26-JAN-2023 (Last updated, Version 16)
Name MhpD
Scope
Bacteria; Pseudomonadota
Template P77608 (MHPD_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MHPD
Protein name
RecName: Full=2-keto-4-pentenoate hydratase;
EC 4.2.1.80;
AltName: Full=2-hydroxypentadienoic acid hydratase;
Gene name
mhpD

Comments [?]

Function Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
Catalytic activity RHEA:22580: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O
EC 4.2.1.80
Cofactor a divalent metal cation
Pathway Aromatic compound metabolism; 3-phenylpropanoate degradation.
Similarity Belongs to the hydratase/decarboxylase family. MhpD subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008684; Molecular function: 2-oxopent-4-enoate hydratase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam PF01557; FAA_hydrolase; 1;

Additional information [?]

Size range 260-271 amino acids
Related rules None
Fusion None