HAMAP rule MF_01655

General rule information [?]

Accession	MF_01655
Dates	30-APR-2008 (Created) 26-JAN-2023 (Last updated, Version 16)

Name

MhpD

Scope

Bacteria; Pseudomonadota

Template

P77608 (MHPD_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MHPD

Protein name

RecName:		Full=2-keto-4-pentenoate hydratase;
		EC 4.2.1.80;
AltName:		Full=2-hydroxypentadienoic acid hydratase;

Gene name

mhpD

Comments [?]

Function	Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
Catalytic activity	RHEA:22580: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O EC 4.2.1.80
Cofactor	a divalent metal cation
Pathway	Aromatic compound metabolism; 3-phenylpropanoate degradation.
Similarity	Belongs to the hydratase/decarboxylase family. MhpD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008684; Molecular function: 2-oxopent-4-enoate hydratase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Cross-references [?]

Pfam	PF01557; FAA_hydrolase; 1;

Additional information [?]