HAMAP rule MF_01655

General rule information [?]

Accession	MF_01655
Dates	30-APR-2008 (Created) 12-MAR-2024 (Last updated, Version 17)
Name	MhpD
Scope(s)	Bacteria Pseudomonadota
Template(s)	P77608 (MHPD_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01655 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MHPD
Protein name	RecName: Full=2-keto-4-pentenoate hydratase; EC=4.2.1.80; AltName: Full=2-hydroxypentadienoic acid hydratase;
Gene name	Name=mhpD;

Comments [?]

FUNCTION	Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
CATALYTIC ACTIVITY	Reaction=(S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4- dienoate + H2O; Xref=Rhea:RHEA:22580, ChEBI:CHEBI:15377, ChEBI:CHEBI:67152, ChEBI:CHEBI:73143; EC=4.2.1.80;
COFACTOR	Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
PATHWAY	Aromatic compound metabolism; 3-phenylpropanoate degradation.
SIMILARITY	Belongs to the hydratase/decarboxylase family. MhpD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008684; Molecular function:2-oxopent-4-enoate hydratase activity

GO:0019380; Biological process:3-phenylpropionate catabolic process

Cross-references [?]

Pfam	PF01557; FAA_hydrolase; 1;

Features [?]

Additional information [?]