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| Annotation rule MF_01655 |
General rule information
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| Accession | MF_01655 |
| Dates | 30-APR-2008 (Created) 19-NOV-2019 (Last updated, Version 15) |
| Name | MhpD |
| Scope | Bacteria; Proteobacteria |
| Template | P77608 (MHPD_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. |
| Catalytic activity | RHEA:22580: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O
EC 4.2.1.80 |
| Cofactor | a divalent metal cation |
| Pathway | Aromatic compound metabolism; 3-phenylpropanoate degradation. |
| Similarity | Belongs to the hydratase/decarboxylase family. MhpD subfamily. |
Keywords
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Gene Ontology
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GO:0008684; Molecular function: 2-oxopent-4-enoate hydratase activity.
GO:0019439; Biological process: aromatic compound catabolic process.
GO:0019439; Biological process: aromatic compound catabolic process.
Cross-references
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| Pfam | PF01557; FAA_hydrolase; 1; |
Additional information
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| Size range | 260-271 amino acids |
| Related rules | None |
| Fusion | None |