HAMAP rule MF_01655
General rule information
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Accession | MF_01655 |
Dates | 30-APR-2008 (Created)
12-MAR-2024 (Last updated, Version 17) |
Name | MhpD |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P77608 (MHPD_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_01655 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | MHPD |
Protein name | RecName: Full=2-keto-4-pentenoate hydratase; EC=4.2.1.80; AltName: Full=2-hydroxypentadienoic acid hydratase; |
Gene name | Name=mhpD; |
Comments
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FUNCTION | Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. |
CATALYTIC ACTIVITY | Reaction=(S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4- dienoate + H2O; Xref=Rhea:RHEA:22580, ChEBI:CHEBI:15377, ChEBI:CHEBI:67152, ChEBI:CHEBI:73143; EC=4.2.1.80; |
COFACTOR | Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; |
PATHWAY | Aromatic compound metabolism; 3-phenylpropanoate degradation. |
SIMILARITY | Belongs to the hydratase/decarboxylase family. MhpD subfamily. |
Keywords
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Gene Ontology
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GO:0008684; Molecular function:2-oxopent-4-enoate hydratase activity |
GO:0019380; Biological process:3-phenylpropionate catabolic process |
Cross-references
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Pfam | PF01557; FAA_hydrolase; 1; |
Features
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Additional information
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Size range | 260-271 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |