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HAMAP rule MF_01655

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General rule information [?]

Accession MF_01655
Dates 30-APR-2008 (Created)
12-MAR-2024 (Last updated, Version 17)
Name MhpD
Scope(s) Bacteria
Template(s) P77608 (MHPD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01655 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MHPD
Protein name RecName: Full=2-keto-4-pentenoate hydratase;
AltName: Full=2-hydroxypentadienoic acid hydratase;
Gene name Name=mhpD;

Comments [?]

FUNCTIONCatalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.
CATALYTIC ACTIVITY Reaction=(S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4- dienoate + H2O; Xref=Rhea:RHEA:22580, ChEBI:CHEBI:15377, ChEBI:CHEBI:67152, ChEBI:CHEBI:73143; EC=;
COFACTOR Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
PATHWAYAromatic compound metabolism; 3-phenylpropanoate degradation.
SIMILARITYBelongs to the hydratase/decarboxylase family. MhpD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008684; Molecular function:2-oxopent-4-enoate hydratase activity
GO:0019380; Biological process:3-phenylpropionate catabolic process

Cross-references [?]

Pfam PF01557; FAA_hydrolase; 1;

Features [?]

Additional information [?]

Size range 260-271 amino acids
Related rules None
Fusion Nter: None Cter: None

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