HAMAP rule MF_01658
General rule information
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| Accession | MF_01658 |
| Dates | 7-MAY-2008 (Created)
26-JAN-2023 (Last updated, Version 18) |
| Name | COQ7 |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | Q9I5R6 (COQ7_PSEAE); Q2RNK3 (COQ7_RHORT); [ Recover all ] |
| Triggered by |
case c? <OC:Pseudomonadota>
HAMAP; MF_01658 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | COQ7 |
| Protein name | RecName: Full=3-demethoxyubiquinol 3-hydroxylase; Short=DMQ hydroxylase; EC=1.14.99.60; AltName: Full=2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; |
| Gene name | Name=coq7; |
Comments
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| FUNCTION | Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. |
| CATALYTIC ACTIVITY | Reaction=a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O; Xref=Rhea:RHEA:50908, Rhea:RHEA-COMP:10859, Rhea:RHEA-COMP:10914, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:17499, ChEBI:CHEBI:84167, ChEBI:CHEBI:84422; EC=1.14.99.60; |
| COFACTOR | Name=Fe cation; Xref=ChEBI:CHEBI:24875; Note=Binds 2 iron ions per subunit.; |
| PATHWAY | Cofactor biosynthesis; ubiquinone biosynthesis. |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| SIMILARITY | Belongs to the COQ7 family. |
Keywords
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Gene Ontology
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| GO:0006744; Biological process:ubiquinone biosynthetic process |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF03232; COQ7; 1; |
Features
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| From: COQ7_PSEAE (Q9I5R6) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 64 | 64 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
E | ||||||||
| BINDING | 94 | 94 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
E | ||||||||
| BINDING | 94 | 94 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
E | ||||||||
| BINDING | 97 | 97 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
H | ||||||||
| BINDING | 146 | 146 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
E | ||||||||
| BINDING | 178 | 178 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
E | ||||||||
| BINDING | 178 | 178 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
E | ||||||||
| BINDING | 181 | 181 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
H | ||||||||
Additional information
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| Size range | 160-250 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |