HAMAP rule MF_01662
General rule information
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| Accession | MF_01662 |
| Dates | 25-JUN-2008 (Created)
26-JAN-2023 (Last updated, Version 18) |
| Name | L_fucose_rotase |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P0AEN8 (FUCM_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01662 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | FUCM |
| Protein name | RecName: Full=L-fucose mutarotase; EC=5.1.3.29; AltName: Full=Fucose 1-epimerase; AltName: Full=Type-2 mutarotase; |
| Gene name | Name=fucU; |
Comments
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| FUNCTION | Involved in the anomeric conversion of L-fucose. |
| CATALYTIC ACTIVITY | Reaction=alpha-L-fucose = beta-L-fucose; Xref=Rhea:RHEA:25580, ChEBI:CHEBI:42548, ChEBI:CHEBI:42589; EC=5.1.3.29; |
| PATHWAY | Carbohydrate metabolism; L-fucose metabolism. |
| SUBUNIT | Homodecamer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the RbsD / FucU family. FucU mutarotase subfamily. |
Keywords
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Gene Ontology
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| GO:0016853; Molecular function:isomerase activity |
| GO:0042354; Biological process:L-fucose metabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF05025; RbsD_FucU; 1; |
Features
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| From: FUCM_ECOLI (P0AEN8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 129 | 131 | /ligand="substrate" | Y-G-N | ||||||||
| ACT_SITE | 22 | 22 | /note="Proton donor" | H | ||||||||
| BINDING | 30 | 30 | /ligand="substrate" | D | ||||||||
| BINDING | 107 | 107 | /ligand="substrate" | R | ||||||||
Additional information
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| Size range | 139-146 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |