HAMAP rule MF_01673

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01673
Accession	MF_01673
Dates	29-SEP-2008 (Created) 13-JAN-2023 (Last updated, Version 12)
Name	IolB
Scope(s)	Bacteria Bacillota
Template(s)	P42413; [ Recover all ]
Triggered by	HAMAP; MF_01673 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	IOLB
Protein name	RecName: Full=5-deoxy-glucuronate isomerase; Short=5DG isomerase; EC=5.3.1.30;
Gene name	Name=iolB;

Comments [?]

FUNCTION	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
CATALYTIC ACTIVITY	Reaction=5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate; Xref=Rhea:RHEA:25840, ChEBI:CHEBI:16669, ChEBI:CHEBI:58852; EC=5.3.1.30;
PATHWAY	Polyol metabolism; myo-inositol degradation into acetyl-CoA; acetyl-CoA from myo-inositol: step 4/7.
SIMILARITY	Belongs to the isomerase IolB family.

Keywords [?]

Gene Ontology [?]

GO:0016861; Molecular function:intramolecular oxidoreductase activity, interconverting aldoses and ketoses

GO:0019310; Biological process:inositol catabolic process

Cross-references [?]

Pfam	PF04962; KduI; 1;

Features [?]

Additional information [?]