HAMAP rule MF_01677
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01677 |
| Accession | MF_01677 |
| Dates | 15-OCT-2008 (Created)
19-SEP-2024 (Last updated, Version 27) |
| Name | Salvage_MtnB |
| Scope(s) |
Bacteria |
| Template(s) | O31668; [ Recover all ] |
| Triggered by |
HAMAP; MF_01677 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MTNB |
| Protein name | RecName: Full=Methylthioribulose-1-phosphate dehydratase; Short=MTRu-1-P dehydratase; EC=4.2.1.109; |
| Gene name | Name=mtnB; |
Comments
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| FUNCTION | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). |
| CATALYTIC ACTIVITY | Reaction=5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl- 2,3-dioxopentyl phosphate + H2O; Xref=Rhea:RHEA:15549, ChEBI:CHEBI:15377, ChEBI:CHEBI:58548, ChEBI:CHEBI:58828; EC=4.2.1.109; |
| COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.; |
| PATHWAY | Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6. |
| case <OC:Bacillaceae> | |
| SUBUNIT | Homotetramer. |
| end case | |
| SIMILARITY | Belongs to the aldolase class II family. MtnB subfamily. |
Keywords
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Gene Ontology
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| GO:0008270; Molecular function:zinc ion binding |
| GO:0046570; Molecular function:methylthioribulose 1-phosphate dehydratase activity |
| GO:0019509; Biological process:L-methionine salvage from methylthioadenosine |
Cross-references
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Features
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| From: MTNB_BACSU (O31668) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 98 | 98 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H | ||||||||
| BINDING | 100 | 100 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H | ||||||||
Additional information
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| Size range | 194-250 amino acids |
| Related rules |
None |
| Fusion | Nter: MF_01680 (mtnX) Cter: None |