HAMAP rule MF_01677
General rule information
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Accession | MF_01677 |
Dates | 15-OCT-2008 (Created)
30-APR-2024 (Last updated, Version 24) |
Name | Salvage_MtnB |
Scope(s) |
Bacteria |
Template(s) | O31668 (MTNB_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_01677 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | MTNB |
Protein name | RecName: Full=Methylthioribulose-1-phosphate dehydratase; Short=MTRu-1-P dehydratase; EC=4.2.1.109; |
Gene name | Name=mtnB; |
Comments
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FUNCTION | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). |
CATALYTIC ACTIVITY | Reaction=S-methyl-5-thio-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3- dioxopentyl phosphate + H2O; Xref=Rhea:RHEA:15549, ChEBI:CHEBI:15377, ChEBI:CHEBI:58548, ChEBI:CHEBI:58828; EC=4.2.1.109; |
COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.; |
PATHWAY | Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6. |
case <OC:Bacillaceae> | |
SUBUNIT | Homotetramer. |
end case | |
SIMILARITY | Belongs to the aldolase class II family. MtnB subfamily. |
Keywords
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Gene Ontology
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GO:0008270; Molecular function:zinc ion binding |
GO:0046570; Molecular function:methylthioribulose 1-phosphate dehydratase activity |
GO:0019509; Biological process:L-methionine salvage from methylthioadenosine |
Cross-references
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Features
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From: MTNB_BACSU (O31668) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 98 | 98 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H | ||||||||
BINDING | 100 | 100 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H |
Additional information
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Size range | 194-250 amino acids |
Related rules |
None |
Fusion | Nter: MF_01680 (mtnX) Cter: None |