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HAMAP rule MF_01677

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General rule information [?]

Accession MF_01677
Dates 15-OCT-2008 (Created)
1-JUN-2023 (Last updated, Version 23)
Name Salvage_MtnB
Scope(s) Bacteria
Template(s) O31668 (MTNB_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01677 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MTNB
Protein name RecName: Full=Methylthioribulose-1-phosphate dehydratase;
                 Short=MTRu-1-P dehydratase;
Gene name Name=mtnB;

Comments [?]

FUNCTIONCatalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
CATALYTIC ACTIVITY Reaction=S-methyl-5-thio-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3- dioxopentyl phosphate + H2O; Xref=Rhea:RHEA:15549, ChEBI:CHEBI:15377, ChEBI:CHEBI:58548, ChEBI:CHEBI:58828; EC=;
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
PATHWAYAmino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
case <OC:Bacillaceae>
end case
SIMILARITYBelongs to the aldolase class II family. MtnB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008270; Molecular function:zinc ion binding
GO:0046570; Molecular function:methylthioribulose 1-phosphate dehydratase activity
GO:0019284; Biological process:L-methionine salvage from S-adenosylmethionine

Cross-references [?]

Pfam PF00596; Aldolase_II; 1;
NCBIfam TIGR03328; Salvage_mtnB; 1;

Features [?]

From: MTNB_BACSU (O31668)
Key From To Description Tag Condition FTGroup
BINDING 98 98 /ligand="Zn(2+)"
BINDING 100 100 /ligand="Zn(2+)"

Additional information [?]

Size range 194-250 amino acids
Related rules None
Fusion Nter: MF_01680 (mtnX) Cter: None

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