HAMAP rule MF_01680
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01680 |
| Accession | MF_01680 |
| Dates | 23-OCT-2008 (Created)
30-APR-2024 (Last updated, Version 17) |
| Name | Salvage_MtnX |
| Scope(s) |
Bacteria Microcystis Bacillota |
| Template(s) | O31667; [ Recover all ] |
| Triggered by |
HAMAP; MF_01680 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MTNX |
| Protein name | RecName: Full=2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase; Short=HK-MTPenyl-1-P phosphatase; EC=3.1.3.87; |
| Gene name | Name=mtnX; |
Comments
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| FUNCTION | Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). |
| CATALYTIC ACTIVITY | Reaction=2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate; Xref=Rhea:RHEA:14481, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:49252, ChEBI:CHEBI:59505; EC=3.1.3.87; |
| PATHWAY | Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6. |
| SIMILARITY | Belongs to the HAD-like hydrolase superfamily. MtnX family. |
Keywords
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Gene Ontology
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| GO:0043716; Molecular function:2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity |
| GO:0019509; Biological process:L-methionine salvage from methylthioadenosine |
Cross-references
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| Pfam | PF06888; Put_Phosphatase; 1; |
| Pfam | PF00702; Hydrolase; 1; |
| NCBIfam | TIGR01489; DKMTPPase-SF; 1; |
| NCBIfam | TIGR01488; HAD-SF-IB; 1; |
| NCBIfam | TIGR03333; Salvage_mtnX; 1; |
Features
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Additional information
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| Size range | 206-427 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: MF_01677 (mtnB) |