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HAMAP rule MF_01689

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General rule information [?]

Accession MF_01689
Dates 1-APR-2009 (Created)
1-JUN-2023 (Last updated, Version 12)
Name Ornith_aminotrans_3
Scope
Bacteria
Template P38021 (OAT_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
OAT
Protein name
RecName: Full=Ornithine aminotransferase;
Short=OAT;
EC 2.6.1.13;
AltName: Full=Ornithine--oxo-acid aminotransferase;
Gene name
rocD

Comments [?]

Function Catalyzes the interconversion of ornithine to glutamate semialdehyde.
Catalytic activity RHEA:13877: a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-glutamate 5-semialdehyde
EC 2.6.1.13
Cofactor pyridoxal 5'-phosphate
Pathway Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.
Subcellular location Cytoplasm.
Similarity Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.

Keywords [?]


Gene Ontology [?]

GO:0004587; Molecular function: ornithine-oxo-acid transaminase activity.
GO:0008483; Molecular function: transaminase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0006561; Biological process: proline biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam PF00202; Aminotran_3; 1;
NCBIfam TIGR01885; Orn_aminotrans; 1;

Features [?]

From: OAT_BACSU (P38021)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     258     258       N6-(pyridoxal phosphate)lysine     K  

Additional information [?]

Size range 394-411 amino acids
Related rules MF_01107 (ARGD)
Fusion None