HAMAP rule MF_01689
General rule information
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| Accession | MF_01689 |
| Dates | 1-APR-2009 (Created)
13-OCT-2023 (Last updated, Version 13) |
| Name | Ornith_aminotrans_3 |
| Scope(s) |
Bacteria |
| Template(s) | P38021 (OAT_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_01689 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | OAT |
| Protein name | RecName: Full=Ornithine aminotransferase; Short=OAT; EC=2.6.1.13; AltName: Full=Ornithine--oxo-acid aminotransferase; |
| Gene name | Name=rocD; |
Comments
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| FUNCTION | Catalyzes the interconversion of ornithine to glutamate semialdehyde. |
| CATALYTIC ACTIVITY | Reaction=a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L- glutamate 5-semialdehyde; Xref=Rhea:RHEA:13877, ChEBI:CHEBI:35179, ChEBI:CHEBI:46911, ChEBI:CHEBI:58066, ChEBI:CHEBI:59869; EC=2.6.1.13; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| PATHWAY | Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily. |
Keywords
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| Amino-acid biosynthesis |
| Aminotransferase |
| Cytoplasm |
| Proline biosynthesis |
| Pyridoxal phosphate |
| Transferase |
Gene Ontology
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| GO:0004587; Molecular function:ornithine aminotransferase activity |
| GO:0008483; Molecular function:transaminase activity |
| GO:0030170; Molecular function:pyridoxal phosphate binding |
| GO:0006561; Biological process:proline biosynthetic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS00600; AA_TRANSFER_CLASS_3; 1; |
| Pfam | PF00202; Aminotran_3; 1; |
| NCBIfam | TIGR01885; Orn_aminotrans; 1; |
Features
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| From: OAT_BACSU (P38021) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 258 | 258 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 394-411 amino acids |
| Related rules |
MF_01107 |
| Fusion | Nter: None Cter: None |