HAMAP rule MF_01689

General rule information [?]

Accession	MF_01689
Dates	1-APR-2009 (Created) 1-JUN-2023 (Last updated, Version 12)

Name	Ornith_aminotrans_3

Scope

Bacteria

Template

P38021 (OAT_BACSU)

Triggered by

HAMAP; MF_01689 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

OAT

Protein name

RecName:		Full=Ornithine aminotransferase;
		Short=OAT;
		EC 2.6.1.13;
AltName:		Full=Ornithine--oxo-acid aminotransferase;

Gene name

rocD

Comments [?]

Function	Catalyzes the interconversion of ornithine to glutamate semialdehyde.
Catalytic activity	RHEA:13877: a 2-oxocarboxylate + L-ornithine = an L-alpha-amino acid + L-glutamate 5-semialdehyde EC 2.6.1.13
Cofactor	pyridoxal 5'-phosphate
Pathway	Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.
Subcellular location	Cytoplasm.
Similarity	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.

Keywords [?]

Amino-acid biosynthesis
Aminotransferase
Cytoplasm
Proline biosynthesis
Pyridoxal phosphate
Transferase

Gene Ontology [?]

GO:0004587; Molecular function: ornithine-oxo-acid transaminase activity.
GO:0008483; Molecular function: transaminase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0006561; Biological process: proline biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS00600; AA_TRANSFER_CLASS_3; 1;
Pfam	PF00202; Aminotran_3; 1;
NCBIfam	TIGR01885; Orn_aminotrans; 1;

Features [?]

From: OAT_BACSU (P38021)

Key From To Description Tag Condition FTGroup

MOD_RES 258 258 N6-(pyridoxal phosphate)lysine K

Additional information [?]

Size range	394-411 amino acids
Related rules	MF_01107 (ARGD)
Fusion	None

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