HAMAP rule MF_01691

General rule information [?]

Accession	MF_01691
Dates	30-APR-2009 (Created) 13-JAN-2023 (Last updated, Version 11)
Name	DapH
Scope(s)	Bacteria Bacillota Thermotogae Archaea
Template(s)	O34981 (DAPH_BACSU); [ Recover all ]
Triggered by	HAMAP; MF_01691 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	DAPH
Protein name	RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; EC=2.3.1.89; AltName: Full=Tetrahydrodipicolinate N-acetyltransferase; Short=THP acetyltransferase; Short=Tetrahydropicolinate acetylase;
Gene name	Name=dapH;

Comments [?]

FUNCTION	Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
CATALYTIC ACTIVITY	Reaction=(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = CoA + L-2-acetamido-6-oxoheptanedioate; Xref=Rhea:RHEA:13085, ChEBI:CHEBI:15377, ChEBI:CHEBI:16845, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:58117; EC=2.3.1.89;
PATHWAY	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3.
SIMILARITY	Belongs to the transferase hexapeptide repeat family. DapH subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016407; Molecular function:acetyltransferase activity

GO:0009089; Biological process:lysine biosynthetic process via diaminopimelate

GO:0019877; Biological process:diaminopimelate biosynthetic process

Cross-references [?]

Features [?]

Additional information [?]