HAMAP rule MF_01691
General rule information
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Accession | MF_01691 |
Dates | 30-APR-2009 (Created)
13-JAN-2023 (Last updated, Version 11) |
Name | DapH |
Scope(s) |
Bacteria Bacillota Thermotogae Archaea |
Template(s) | O34981 (DAPH_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_01691 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | DAPH |
Protein name | RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; EC=2.3.1.89; AltName: Full=Tetrahydrodipicolinate N-acetyltransferase; Short=THP acetyltransferase; Short=Tetrahydropicolinate acetylase; |
Gene name | Name=dapH; |
Comments
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FUNCTION | Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. |
CATALYTIC ACTIVITY | Reaction=(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = CoA + L-2-acetamido-6-oxoheptanedioate; Xref=Rhea:RHEA:13085, ChEBI:CHEBI:15377, ChEBI:CHEBI:16845, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:58117; EC=2.3.1.89; |
PATHWAY | Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3. |
SIMILARITY | Belongs to the transferase hexapeptide repeat family. DapH subfamily. |
Keywords
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Acyltransferase |
Amino-acid biosynthesis |
Diaminopimelate biosynthesis |
Lysine biosynthesis |
Repeat |
Transferase |
Gene Ontology
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GO:0016407; Molecular function:acetyltransferase activity |
GO:0009089; Biological process:lysine biosynthetic process via diaminopimelate |
GO:0019877; Biological process:diaminopimelate biosynthetic process |
Cross-references
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Features
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Additional information
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Size range | 228-257 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |