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HAMAP rule MF_01691

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General rule information [?]

Accession MF_01691
Dates 30-APR-2009 (Created)
13-JAN-2023 (Last updated, Version 11)
Name DapH
Scope(s) Bacteria
Template(s) O34981 (DAPH_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01691 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DAPH
Protein name RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase;
AltName: Full=Tetrahydrodipicolinate N-acetyltransferase;
                 Short=THP acetyltransferase;
                 Short=Tetrahydropicolinate acetylase;
Gene name Name=dapH;

Comments [?]

FUNCTIONCatalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
CATALYTIC ACTIVITY Reaction=(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = CoA + L-2-acetamido-6-oxoheptanedioate; Xref=Rhea:RHEA:13085, ChEBI:CHEBI:15377, ChEBI:CHEBI:16845, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288, ChEBI:CHEBI:58117; EC=;
PATHWAYAmino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3.
SIMILARITYBelongs to the transferase hexapeptide repeat family. DapH subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016407; Molecular function:acetyltransferase activity
GO:0009089; Biological process:lysine biosynthetic process via diaminopimelate
GO:0019877; Biological process:diaminopimelate biosynthetic process

Cross-references [?]

Pfam PF08503; DapH_N; 1;
Pfam PF00132; Hexapep; 4;

Features [?]

Additional information [?]

Size range 228-257 amino acids
Related rules None
Fusion Nter: None Cter: None

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