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HAMAP rule MF_01691

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General rule information [?]

Accession MF_01691
Dates 30-APR-2009 (Created)
13-JAN-2023 (Last updated, Version 11)
Name DapH
Scope
Bacteria; Bacillota
Bacteria; Thermotogae
Archaea
Template O34981 (DAPH_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DAPH
Protein name
RecName: Full=2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase;
EC 2.3.1.89;
AltName: Full=Tetrahydrodipicolinate N-acetyltransferase;
Short=THP acetyltransferase;
Short=Tetrahydropicolinate acetylase;
Gene name
dapH

Comments [?]

Function Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
Catalytic activity RHEA:13085: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = CoA + L-2-acetamido-6-oxoheptanedioate
EC 2.3.1.89
Pathway Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3.
Similarity Belongs to the transferase hexapeptide repeat family. DapH subfamily.

Keywords [?]


Gene Ontology [?]

GO:0016407; Molecular function: acetyltransferase activity.
GO:0009089; Biological process: lysine biosynthetic process via diaminopimelate.
GO:0019877; Biological process: diaminopimelate biosynthetic process.

Cross-references [?]

PROSITE PS00101; HEXAPEP_TRANSFERASES; 1;
Pfam PF08503; DapH_N; 1;
PF00132; Hexapep; 4;

Additional information [?]

Size range 228-257 amino acids
Related rules None
Fusion None