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Annotation rule MF_01707
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General rule information [?]

Accession MF_01707
Dates 11-OCT-2004 (Created)
19-NOV-2019 (Last updated, Version 22)
Name ABC_ATPase_CcmA
Scope
Bacteria; Deinococci
Bacteria; Proteobacteria
Eukaryota; Arabidopsis
Mitochondrion
Template P33931 (CCMA_ECOLI)
Triggered by PROSITE; PS51243

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CCMA
Protein name
RecName: Full=Cytochrome c biogenesis ATP-binding export protein CcmA;
EC 7.6.2.5;
AltName: Full=Heme exporter protein A;
Gene name
ccmA

Comments [?]

case <OC:Bacteria> or <OG:Mitochondrion>
Function Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:19261: ATP + H2O + heme b(in) = ADP + H(+) + heme b(out) + phosphate
EC 7.6.2.5
Subunit The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).
Similarity Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
end case
case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>)
Subcellular location Cell membrane; Peripheral membrane protein.
end case
case <OC:Bacteria> and (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location Cell inner membrane; Peripheral membrane protein.
end case
case <OG:Mitochondrion>
Subcellular location Mitochondrion membrane; Peripheral membrane protein.
end case

Keywords [?]

ATP-binding
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
case <OC:Bacteria>
Cell membrane
end case
Membrane
Nucleotide-binding
Transport
Translocase
Cytochrome c-type biogenesis

Gene Ontology [?]

GO:0022857; Molecular function: transmembrane transporter activity.
GO:0055085; Biological process: transmembrane transport.
case <OC:Bacteria>
GO:0005886; Cellular component: plasma membrane.
end case
case <OG:Mitochondrion>
GO:0031966; Cellular component: mitochondrial membrane.
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
TIGRFAMs TIGR01189; CcmA; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

Additional information [?]

Size range 192-345 amino acids
Related rules PRU01700
Fusion Nter: None; Cter: ccmE


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