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HAMAP rule MF_01728

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General rule information [?]

Accession MF_01728
Dates 14-MAY-2007 (Created)
1-JUN-2023 (Last updated, Version 23)
Name ABC_ATPase_TM_NdvA
Scope(s) Bacteria
Hyphomicrobiales
Template(s) P18767 (NDVA_RHIME); [ Recover all ]
Triggered by PROSITE; PS51317 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NDVA
Protein name RecName: Full=Beta-(1-->2)glucan export ATP-binding/permease protein NdvA;
                 EC=7.5.2.3;
Gene name Name=ndvA;

Comments [?]

FUNCTIONInvolved in Beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
CATALYTIC ACTIVITY Reaction=[(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O = [(1->2)-beta-D- glucosyl](n)(out) + ADP + H(+) + phosphate; Xref=Rhea:RHEA:18453, Rhea:RHEA-COMP:11881, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:27517, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.5.2.3;
SUBUNITHomodimer.
DOMAINIn NdvA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Beta- (1-->2)glucan exporter (TC 3.A.1.108.1) family.

Keywords [?]

ATP-binding
Nucleotide-binding
Cell membrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Membrane
Sugar transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0008643; Biological process:carbohydrate transport
GO:0015441; Molecular function:ABC-type beta-glucan transporter activity
case <OCellular component:Bacteria>
GO:0005886; Cellular component:plasma membrane
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
Pfam PF00664; ABC_membrane; 1;
NCBIfam TIGR01192; ChvA; 1;
PROSITE PS50929; ABC_TM1F; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]


Additional information [?]

Size range 550-630 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



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