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Annotation rule MF_01803 |
Accession | MF_01803 |
Dates | 9-JAN-2004 (Created) 19-NOV-2019 (Last updated, Version 24) |
Name | MukF |
Scope | Bacteria; Gammaproteobacteria |
Template | P60293 (MUKF_ECOLI) |
Triggered by |
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Function | Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. |
Subunit | Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB. |
Subcellular location | Cytoplasm, nucleoid. Note=Restricted to the nucleoid region. |
Similarity | Belongs to the MukF family. |
Pfam | PF03882; KicB; 1; |
From: MUKF_ECOLI (P60293) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 208 | 236 | Leucine-zipper | L-x(6)-L-x(6)-L-x(6)-L-x(6)-[LI] |
Size range | 440-445 amino acids |
Related rules | None |
Fusion | None |