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Annotation rule MF_01803
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General rule information [?]

Accession MF_01803
Dates 9-JAN-2004 (Created)
19-NOV-2019 (Last updated, Version 24)
Name MukF
Scope
Bacteria; Gammaproteobacteria
Template P60293 (MUKF_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MUKF
Protein name
RecName: Full=Chromosome partition protein MukF;
Gene name
mukF

Comments [?]

Function Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
Subunit Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
Subcellular location Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Similarity Belongs to the MukF family.

Keywords [?]

Cytoplasm
Cell cycle
Cell division
Chromosome partition
DNA condensation
Calcium

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0006260; Biological process: DNA replication.
GO:0007059; Biological process: chromosome segregation.
GO:0005509; Molecular function: calcium ion binding.

Cross-references [?]

Pfam PF03882; KicB; 1;

Features [?]

From: MUKF_ECOLI (P60293)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     208     236       Leucine-zipper     L-x(6)-L-x(6)-L-x(6)-L-x(6)-[LI]  

Additional information [?]

Size range 440-445 amino acids
Related rules None
Fusion None


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