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HAMAP rule MF_01803

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General rule information [?]

Accession MF_01803
Dates 9-JAN-2004 (Created)
19-NOV-2019 (Last updated, Version 24)
Name MukF
Scope(s) Bacteria
Template(s) P60293 (MUKF_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01803 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MUKF
Protein name RecName: Full=Chromosome partition protein MukF;
Gene name Name=mukF;

Comments [?]

FUNCTIONInvolved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
SUBUNITInteracts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
SUBCELLULAR LOCATIONCytoplasm, nucleoid. Note=Restricted to the nucleoid region.
SIMILARITYBelongs to the MukF family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0006260; Biological process:DNA replication
GO:0007059; Biological process:chromosome segregation
GO:0005509; Molecular function:calcium ion binding

Cross-references [?]

Pfam PF03882; KicB; 1;

Features [?]

From: MUKF_ECOLI (P60293)
Key From To Description Tag Condition FTGroup
REGION 208 236 /note="Leucine-zipper" L-x(6)-L-x(6)-L-x(6)-L-x(6)-[LI]

Additional information [?]

Size range 440-445 amino acids
Related rules None
Fusion Nter: None Cter: None

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