HAMAP rule MF_01805

General rule information [?]

Accession	MF_01805
Dates	17-DEC-2003 (Created) 13-JAN-2023 (Last updated, Version 16)

Name

ScpA

Scope

Bacteria; Bacillota

Template

P35154 (SCPA_BACSU)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

SCPA

Protein name

RecName:

Full=Segregation and condensation protein A;

Gene name

scpA

Comments [?]

Function	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
Subunit	Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
Subcellular location	Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Similarity	Belongs to the ScpA family.

Keywords [?]

Gene Ontology [?]

GO:0006260; Biological process: DNA replication.
GO:0007059; Biological process: chromosome segregation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF02616; ScpA_ScpB; 1;

Additional information [?]

Size range	233-300 amino acids
Related rules	None
Fusion	Nter: <dihydrofolate reductase-like>; Cter: None
Comments	In MYCGA, MYCGE and MYCPN the protein is fused in its N-terminus with a domain that is strongly related to the dihydrofolate reductase domain.