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HAMAP rule MF_01805

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General rule information [?]

Accession MF_01805
Dates 17-DEC-2003 (Created)
8-FEB-2024 (Last updated, Version 17)
Name ScpA
Scope(s) Bacteria
Template(s) P35154 (SCPA_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01805 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SCPA
Protein name RecName: Full=Segregation and condensation protein A;
Gene name Name=scpA;

Comments [?]

FUNCTIONParticipates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
SUBUNITComponent of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
SUBCELLULAR LOCATIONCytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
SIMILARITYBelongs to the ScpA family.

Keywords [?]

Gene Ontology [?]

GO:0006260; Biological process:DNA replication
GO:0007059; Biological process:chromosome segregation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02616; ScpA_ScpB; 1;

Features [?]

Additional information [?]

Size range 233-300 amino acids
Related rules None
Fusion Nter: <dihydrofolate reductase-like> Cter: None
Comments In MYCGA, MYCGE and MYCPN the protein is fused in its N-terminus with a domain that is strongly related to the dihydrofolate reductase domain.

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