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| Annotation rule MF_01805 |
General rule information
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| Accession | MF_01805 |
| Dates | 17-DEC-2003 (Created) 19-NOV-2019 (Last updated, Version 15) |
| Name | ScpA |
| Scope | Bacteria; Firmicutes |
| Template | P35154 (SCPA_BACSU) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. |
| Subunit | Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA. |
| Subcellular location | Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells. |
| Similarity | Belongs to the ScpA family. |
Keywords
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Gene Ontology
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GO:0006260; Biological process: DNA replication.
GO:0007059; Biological process: chromosome segregation.
GO:0005737; Cellular component: cytoplasm.
GO:0007059; Biological process: chromosome segregation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF02616; ScpA_ScpB; 1; |
Additional information
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| Size range | 233-300 amino acids |
| Related rules | None |
| Fusion | Nter: <dihydrofolate reductase-like>; Cter: None |
| Comments | In MYCGA, MYCGE and MYCPN the protein is fused in its N-terminus with a domain that is strongly related to the dihydrofolate reductase domain. |