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Annotation rule MF_01811
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General rule information [?]

Accession MF_01811
Dates 17-NOV-2003 (Created)
19-NOV-2019 (Last updated, Version 23)
Name YidC_type2
Scope
Bacteria; Firmicutes
Templates Q01625 (MISCA_BACSU); P54544 (MISCB_BACSU); Q8DVX3 (YIDC1_STRMU); Q8DSP8 (YIDC2_STRMU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
YIDC
Protein name
RecName: Full=Membrane protein insertase YidC;
AltName: Full=Foldase YidC;
AltName: Full=Membrane protein YidC;
AltName: Full=Membrane integrase YidC;
Flags: Precursor;
Gene name
yidC

Comments [?]

Function Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
Subcellular location Cell membrane; Multi-pass membrane protein.
Similarity Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.

Keywords [?]

case <Feature:PS51257>
end case

Gene Ontology [?]

GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF02096; 60KD_IMP; 1;
PRINTS PR00701; 60KDINNERMP; 1;
TIGRFAMs TIGR03592; YidC_oxa1_C; 1;
PROSITE PS51257; PROKAR_LIPOPROTEIN; 1; trigger=PRU00303;

Computed features [?]

General Transmembrane; -; 4-6; trigger=yes;

Additional information [?]

Size range 252-320 amino acids
Related rules MF_01810 (YIDC)
Fusion None
Comments This family, which is specific to most Firmicutes, is closely related to the protein family (MF_01810) and displays a similar function. These proteins, which are often present in two copies, are however much shorter than MF_01810 proteins, and are probably lipoproteins. In the 2 organisms in which they have been studied they have overlapping but not identical functions.