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| Annotation rule MF_01811 |
General rule information
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| Accession | MF_01811 |
| Dates | 17-NOV-2003 (Created) 4-JUN-2021 (Last updated, Version 24) |
| Name | YidC_type2 |
| Scope | Bacteria; Firmicutes |
| Templates | Q01625 (MISCA_BACSU); P54544 (MISCB_BACSU); Q8DVX3 (YIDC1_STRMU); Q8DSP8 (YIDC2_STRMU): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Similarity | Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. |
Keywords
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case <Feature:PS51257>
end case
Gene Ontology
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GO:0005886; Cellular component: plasma membrane.
Cross-references
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| Pfam | PF02096; 60KD_IMP; 1; |
| PRINTS | PR00701; 60KDINNERMP; 1; |
| TIGRFAMs | TIGR03592; YidC_oxa1_C; 1; |
| PROSITE | PS51257; PROKAR_LIPOPROTEIN; 1; trigger=PRU00303; |
Computed features
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| General | Transmembrane; -; 4-6; trigger=yes; |
Additional information
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| Size range | 252-320 amino acids |
| Related rules | MF_01810 (YIDC) |
| Fusion | None |
| Comments | This family, which is specific to most Firmicutes, is closely related to the protein family (MF_01810) and displays a similar function. These proteins, which are often present in two copies, are however much shorter than MF_01810 proteins, and are probably lipoproteins. In the 2 organisms in which they have been studied they have overlapping but not identical functions. |