HAMAP rule MF_01811
General rule information
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| Accession | MF_01811 |
| Dates | 17-NOV-2003 (Created)
1-JUN-2023 (Last updated, Version 27) |
| Name | YidC_type2 |
| Scope(s) |
Bacteria Bacillota |
| Template(s) | Q01625 (MISCA_BACSU); P54544 (MISCB_BACSU); Q8DVX3 (YIDC1_STRMU); Q8DSP8 (YIDC2_STRMU); [ Recover all ] |
| Triggered by |
HAMAP; MF_01811 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | YIDC |
| Protein name | RecName: Full=Membrane protein insertase YidC; AltName: Full=Foldase YidC; AltName: Full=Membrane protein YidC; AltName: Full=Membrane integrase YidC; Flags: Precursor; |
| Gene name | Name=yidC; |
Comments
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| FUNCTION | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. |
Keywords
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| Membrane | |
| Cell membrane | |
| Chaperone | |
| Protein transport | |
| Transmembrane | |
| Transport | |
| case <Feature:PS51257> | |
| Lipoprotein | |
| end case | |
| Signal | |
| Transmembrane helix | |
Gene Ontology
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| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02096; 60KD_IMP; 1; |
| PRINTS | PR00701; 60KDINNERMP; 1; |
| NCBIfam | TIGR03592; YidC_oxa1_C; 1; |
| PROSITE | PS51257; PROKAR_LIPOPROTEIN; 1; |
| General | Transmembrane; -; 4-6; |
Features
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Additional information
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| Size range | 252-320 amino acids |
| Related rules |
MF_01810 |
| Fusion | Nter: None Cter: None |
| Comments | This family, which is specific to most Bacillota, is closely related to the protein family (MF_01810) and displays a similar function. These proteins, which are often present in two copies, are however much shorter than MF_01810 proteins, and are probably lipoproteins. In the 2 organisms in which they have been studied they have overlapping but not identical functions. |