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HAMAP rule MF_01811

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General rule information [?]

Accession MF_01811
Dates 17-NOV-2003 (Created)
1-JUN-2023 (Last updated, Version 27)
Name YidC_type2
Scope(s) Bacteria
Template(s) Q01625 (MISCA_BACSU); P54544 (MISCB_BACSU); Q8DVX3 (YIDC1_STRMU); Q8DSP8 (YIDC2_STRMU); [ Recover all ]
Triggered by HAMAP; MF_01811 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier YIDC
Protein name RecName: Full=Membrane protein insertase YidC;
AltName: Full=Foldase YidC;
AltName: Full=Membrane protein YidC;
AltName: Full=Membrane integrase YidC;
                 Flags: Precursor;
Gene name Name=yidC;

Comments [?]

FUNCTIONRequired for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the OXA1/ALB3/YidC family. Type 2 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF02096; 60KD_IMP; 1;
NCBIfam TIGR03592; YidC_oxa1_C; 1;
General Transmembrane; -; 4-6;

Features [?]

Additional information [?]

Size range 252-320 amino acids
Related rules MF_01810
Fusion Nter: None Cter: None
Comments This family, which is specific to most Bacillota, is closely related to the protein family (MF_01810) and displays a similar function. These proteins, which are often present in two copies, are however much shorter than MF_01810 proteins, and are probably lipoproteins. In the 2 organisms in which they have been studied they have overlapping but not identical functions.

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