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HAMAP rule MF_01832

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General rule information [?]

Accession MF_01832
Dates 30-SEP-2004 (Created)
19-NOV-2019 (Last updated, Version 17)
Name SufE
Scope(s) Bacteria
Template(s) P76194 (SUFE_ECOLI); Q9EXP1 (SUFE_DICD3); [ Recover all ]
Triggered by HAMAP; MF_01832 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SUFE
Protein name RecName: Full=Cysteine desulfuration protein SufE;
Gene name Name=sufE;

Comments [?]

FUNCTIONParticipates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
PATHWAYCofactor biosynthesis; iron-sulfur cluster biosynthesis.
SUBUNITHomodimer. Interacts with SufS.
SIMILARITYBelongs to the SufE family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02657; SufE; 1;

Features [?]

From: SUFE_ECOLI (P76194)
Key From To Description Tag Condition FTGroup
ACT_SITE 51 51 /note="Cysteine persulfide intermediate" C

Additional information [?]

Size range 138-144 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The suf operon encodes a minor pathway of Fe-S cluster, which is probably activated and required only in specific stressfull conditions such as oxidative stress and/or iron limitation.

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