HAMAP rule MF_01839

General rule information [?]

Accession	MF_01839
Dates	28-JUL-2005 (Created) 19-NOV-2019 (Last updated, Version 16)
Name	NO_factor_SlmA
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P0C093 (SLMA_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_01839 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	SLMA
Protein name	RecName: Full=Nucleoid occlusion factor SlmA;
Gene name	Name=slmA;

Comments [?]

FUNCTION	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
SUBUNIT	Homodimer. Interacts with FtsZ.
SUBCELLULAR LOCATION	Cytoplasm, nucleoid.
SIMILARITY	Belongs to the nucleoid occlusion factor SlmA family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0043590; Cellular component:bacterial nucleoid

GO:0051302; Biological process:regulation of cell division

GO:0043565; Molecular function:sequence-specific DNA binding

GO:0005515; Molecular function:protein binding

Cross-references [?]

Features [?]

Additional information [?]

Size range	195-218 amino acids
Related rules	None
Fusion	Nter: None Cter: None
Comments	Although SlmA is a member of the TetR family, it does not exert its function via transcription regulation (PubMed:21113127).