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HAMAP rule MF_01841

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General rule information [?]

Accession MF_01841
Dates 28-JUL-2005 (Created)
7-MAY-2024 (Last updated, Version 23)
Name Agmatine_deimin
Scope(s) Bacteria
Template(s) Q9I6J9 (AGUA_PSEAE); [ Recover all ]
Triggered by HAMAP; MF_01841 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AGUA
case <OC:Pseudomonadales>
Protein name RecName: Full=Agmatine deiminase;
                 EC=3.5.3.12;
AltName: Full=Agmatine iminohydrolase;
end case
case not <OC:Pseudomonadales>
Protein name RecName: Full=Putative agmatine deiminase;
                 EC=3.5.3.12;
AltName: Full=Agmatine iminohydrolase;
end case
Gene name Name=aguA;

Comments [?]

case <OC:Pseudomonadales>
FUNCTIONMediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
CATALYTIC ACTIVITY Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12;
PATHWAYAmine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; N-carbamoylputrescine from agmatine: step 1/1.
SUBUNITHomodimer.
end case
case not <OC:Pseudomonadales>
CATALYTIC ACTIVITY Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12;
end case
SIMILARITYBelongs to the agmatine deiminase family.

Keywords [?]

Hydrolase
case <OC:Pseudomonadales>
Polyamine biosynthesis
end case

Gene Ontology [?]

GO:0047632; Molecular function:agmatine deiminase activity
case <OCellular component:Pseudomonadales>
GO:0033388; Biological process:putrescine biosynthetic process from arginine
end case

Cross-references [?]

Pfam PF04371; PAD_porph; 1;

Features [?]

From: AGUA_PSEAE (Q9I6J9)
Key From To Description Tag Condition FTGroup
ACT_SITE 357 357 /note="Amidino-cysteine intermediate" C

Additional information [?]

Size range 339-371 amino acids
Related rules None
Fusion Nter: None Cter: None



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