HAMAP rule MF_01841
General rule information
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| Accession | MF_01841 |
| Dates | 28-JUL-2005 (Created)
19-NOV-2019 (Last updated, Version 22) |
| Name | Agmatine_deimin |
| Scope(s) |
Bacteria |
| Template(s) | Q9I6J9 (AGUA_PSEAE); [ Recover all ] |
| Triggered by |
HAMAP; MF_01841 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | AGUA |
| case <OC:Pseudomonadales> | |
| Protein name | RecName: Full=Agmatine deiminase; EC=3.5.3.12; AltName: Full=Agmatine iminohydrolase; |
| end case | |
| case not <OC:Pseudomonadales> | |
| Protein name | RecName: Full=Putative agmatine deiminase; EC=3.5.3.12; AltName: Full=Agmatine iminohydrolase; |
| end case | |
| Gene name | Name=aguA; |
Comments
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| case <OC:Pseudomonadales> | |
| FUNCTION | Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine. |
| CATALYTIC ACTIVITY | Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12; |
| PATHWAY | Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; N-carbamoylputrescine from agmatine: step 1/1. |
| SUBUNIT | Homodimer. |
| end case | |
| case not <OC:Pseudomonadales> | |
| CATALYTIC ACTIVITY | Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+); Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12; |
| end case | |
| SIMILARITY | Belongs to the agmatine deiminase family. |
Keywords
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| Hydrolase | |
| case <OC:Pseudomonadales> | |
| Polyamine biosynthesis | |
| end case | |
Gene Ontology
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| GO:0047632; Molecular function:agmatine deiminase activity | |
| case <OCellular component:Pseudomonadales> | |
| GO:0009446; Biological process:putrescine biosynthetic process | |
| end case | |
Cross-references
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| Pfam | PF04371; PAD_porph; 1; |
Features
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| From: AGUA_PSEAE (Q9I6J9) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 357 | 357 | /note="Amidino-cysteine intermediate" | C | ||||||||
Additional information
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| Size range | 339-371 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |