HAMAP rule MF_01848

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01848
Accession	MF_01848
Dates	09-JUL-2008 (Created) 02-SEP-2024 (Last updated, Version 17)
Name	23SrRNA_methyltr_F
Scope(s)	Bacteria Bacteroidota Pseudomonadota
Template(s)	P75782; [ Recover all ]
Triggered by	HAMAP; MF_01848 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RLMF
Protein name	RecName: Full=Ribosomal RNA large subunit methyltransferase F; EC=2.1.1.181; AltName: Full=23S rRNA mA1618 methyltransferase; AltName: Full=rRNA adenine N-6-methyltransferase;
Gene name	Name=rlmF;

Comments [?]

FUNCTION	Specifically methylates the adenine in position 1618 of 23S rRNA.
CATALYTIC ACTIVITY	Reaction=adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine = N(6)- methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:16497, Rhea:RHEA-COMP:10229, Rhea:RHEA-COMP:10231, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.181;
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the methyltransferase superfamily. METTL16/RlmF family.

Keywords [?]

Gene Ontology [?]

GO:0008988; Molecular function:rRNA (adenine-N6-)-methyltransferase activity

GO:0006364; Biological process:rRNA processing

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF05971; Methyltransf_10; 1;
PIRSF	PIRSF029038; Mtase_YbiN_prd; 1;

Features [?]

Additional information [?]