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Annotation rule MF_01853
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General rule information [?]

Accession MF_01853
Dates 18-DEC-2008 (Created)
19-NOV-2019 (Last updated, Version 9)
Name PelO
Templates Q9HJ74 (PELO_THEAC); P96026 (PELO_SACS2): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Protein pelota homolog;
EC 3.1.-.-;
Gene name

Comments [?]

Function May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
Cofactor a divalent metal cation
Subunit Monomer.
Subcellular location Cytoplasm.
Domain The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.
Similarity Belongs to the eukaryotic release factor 1 family. Pelota subfamily.

Keywords [?]

Gene Ontology [?]

GO:0004519; Molecular function: endonuclease activity.
GO:0046872; Molecular function: metal ion binding.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF03463; eRF1_1; 1;
PF03464; eRF1_2; 1;
PF03465; eRF1_3; 1;
TIGRFAMs TIGR00111; Pelota; 1;

Additional information [?]

Size range 328-360 amino acids
Related rules None
Fusion None