HAMAP rule MF_01853

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01853
Accession	MF_01853
Dates	18-DEC-2008 (Created) 01-JUN-2023 (Last updated, Version 11)
Name	PelO
Scope(s)	Archaea
Template(s)	Q9HJ74; P96026; [ Recover all ]
Triggered by	HAMAP; MF_01853 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PELO
Protein name	RecName: Full=Protein pelota homolog; EC=3.1.-.-;
Gene name	Name=pelA;

Comments [?]

FUNCTION	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
COFACTOR	Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
SUBUNIT	Monomer.
SUBCELLULAR LOCATION	Cytoplasm.
DOMAIN	The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.
SIMILARITY	Belongs to the eukaryotic release factor 1 family. Pelota subfamily.

Keywords [?]

Gene Ontology [?]

GO:0004519; Molecular function:endonuclease activity

GO:0046872; Molecular function:metal ion binding

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]