HAMAP logo

HAMAP rule MF_01853

Send feedback

General rule information [?]

Accession MF_01853
Dates 18-DEC-2008 (Created)
1-JUN-2023 (Last updated, Version 10)
Name PelO
Scope(s) Archaea
Template(s) Q9HJ74 (PELO_THEAC); P96026 (PELO_SACS2); [ Recover all ]
Triggered by HAMAP; MF_01853 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PELO
Protein name RecName: Full=Protein pelota homolog;
Gene name Name=pelA;

Comments [?]

FUNCTIONMay function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
COFACTOR Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
DOMAINThe N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.
SIMILARITYBelongs to the eukaryotic release factor 1 family. Pelota subfamily.

Keywords [?]

Gene Ontology [?]

GO:0004519; Molecular function:endonuclease activity
GO:0046872; Molecular function:metal ion binding
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF03463; eRF1_1; 1;
Pfam PF03464; eRF1_2; 1;
Pfam PF03465; eRF1_3; 1;
NCBIfam TIGR00111; Pelota; 1;

Features [?]

Additional information [?]

Size range 328-360 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)