HAMAP rule MF_01869

Accession	MF_01869
Dates	22-JUL-2009 (Created) 29-SEP-2022 (Last updated, Version 12)

Name	Flippase_ArnE

Scope

Bacteria; Gammaproteobacteria

Template

Q47377 (ARNE_ECOLI)

Triggered by

HAMAP; MF_01869 (Get profile general information and statistics)

Identifier

ARNE

Protein name

RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnE; AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE;

Gene name

arnE

Function	Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
Subunit	Heterodimer of ArnE and ArnF.
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Similarity	Belongs to the ArnE family.

Cell inner membrane
Cell membrane
Lipid A biosynthesis
Lipid biosynthesis
Lipid metabolism
Lipopolysaccharide biosynthesis
Membrane
Transmembrane
Transport
Transmembrane helix

GO:0009245; Biological process: lipid A biosynthetic process.
GO:0055085; Biological process: transmembrane transport.
GO:0022857; Molecular function: transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.

Pfam	PF00892; EamA; 0-1; trigger=Yes;

General

Transmembrane; -; 2-4; trigger=yes;

Size range	107-120 amino acids
Related rules	None
Fusion	None

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