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Annotation rule MF_01870 |
Accession | MF_01870 |
Dates | 3-AUG-2009 (Created) 19-NOV-2019 (Last updated, Version 12) |
Name | ArnD |
Scope | Bacteria; Gammaproteobacteria |
Template | P76472 (ARND_ECOLI) |
Triggered by |
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Protein name |
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Gene name |
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Function | Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. |
Catalytic activity | RHEA:27734: 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + H2O = 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + formate
EC 3.5.1.n3 |
Pathway | Glycolipid biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2. |
Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. | |
Similarity | Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. |
Size range | 276-310 amino acids |
Related rules | None |
Fusion | None |