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Annotation rule MF_01876 |
Accession | MF_01876 |
Dates | 25-NOV-2009 (Created) 19-NOV-2019 (Last updated, Version 10) |
Name | PsiMP_glycosidase |
Scope | Bacteria |
Templates | P33025 (PSUG_ECOLI); Q9X1H5 (PSUG_THEMA): [Recover all] |
Triggered by |
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Protein name |
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Gene name |
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Function | Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway. |
Catalytic activity | RHEA:18337: D-ribose 5-phosphate + uracil = H2O + psi-UMP
EC 4.2.1.70 |
Cofactor | Mn(2+) Note: Binds 1 Mn(2+) ion per subunit. |
Subunit | Homotrimer. |
Similarity | Belongs to the pseudouridine-5'-phosphate glycosidase family. |
Pfam | PF04227; Indigoidine_A; 1; |
From: PSUG_ECOLI (P33025) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 147 | 149 | Substrate binding | S-x-D | ||||||||
ACT_SITE | 31 | 31 | Proton donor | E | ||||||||
ACT_SITE | 166 | 166 | Nucleophile | K | ||||||||
METAL | 145 | 145 | Manganese | D | ||||||||
BINDING | 93 | 93 | Substrate | K | ||||||||
BINDING | 113 | 113 | Substrate; via amide nitrogen | [VA] |
Size range | 270-369 amino acids |
Related rules | None |
Fusion | None |