HAMAP rule MF_01883

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01883
Accession	MF_01883
Dates	28-JUL-2010 (Created) 01-JUN-2023 (Last updated, Version 10)
Name	MdcB
Scope(s)	Bacteria Pseudomonadota
Template(s)	P71422; [ Recover all ]
Triggered by	HAMAP; MF_01883 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MDCB
case <OC:Enterobacterales>
Protein name	RecName: Full=2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Short=2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase; EC=2.4.2.52;
else
Protein name	RecName: Full=Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Short=2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase; EC=2.4.2.52;
end case
Gene name	Name=mdcB;

Comments [?]

FUNCTION	Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.
CATALYTIC ACTIVITY	Reaction=3'-dephospho-CoA + ATP = 2'-(5''-triphospho-alpha-D-ribosyl)- 3'-dephospho-CoA + adenine; Xref=Rhea:RHEA:15117, ChEBI:CHEBI:16708, ChEBI:CHEBI:30616, ChEBI:CHEBI:57328, ChEBI:CHEBI:61378; EC=2.4.2.52;
SIMILARITY	Belongs to the CitG/MdcB family.

Keywords [?]

Gene Ontology [?]

GO:0046917; Molecular function:triphosphoribosyl-dephospho-CoA synthase activity

Cross-references [?]

Pfam	PF01874; CitG; 1;
NCBIfam	TIGR03132; Malonate_mdcB; 1;

Features [?]

Additional information [?]