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Annotation rule MF_01887
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General rule information [?]

Accession MF_01887
Dates 8-NOV-2010 (Created)
19-NOV-2019 (Last updated, Version 9)
Name 23SrRNA_methyltr_B
Scope
Bacteria; Proteobacteria
Template P63177 (RLMB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RLMB
Protein name
RecName: Full=23S rRNA (guanosine-2'-O-)-methyltransferase RlmB;
EC 2.1.1.185;
AltName: Full=23S rRNA (guanosine2251 2'-O)-methyltransferase;
AltName: Full=23S rRNA Gm2251 2'-O-methyltransferase;
Gene name
rlmB

Comments [?]

Function Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
Catalytic activity RHEA:24140: guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.185
case <OC:Enterobacterales>
Subunit Homodimer.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.

Keywords [?]

Cytoplasm
Methyltransferase
rRNA processing
S-adenosyl-L-methionine
Transferase

Gene Ontology [?]

GO:0070039; Molecular function: rRNA (guanosine-2'-O-)-methyltransferase activity.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00588; SpoU_methylase; 1;
PF08032; SpoU_sub_bind; 1;
TIGRFAMs TIGR00186; RRNA_methyl_3; 1;

Features [?]

From: RLMB_ECOLI (P63177)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     196     196       S-adenosyl-L-methionine; via carbonyl oxygen     G  
BINDING     216     216       S-adenosyl-L-methionine; via amide nitrogen and carbonyl oxygen     [IL]  
BINDING     225     225       S-adenosyl-L-methionine; via amide nitrogen     [LM]  

Additional information [?]

Size range 231-284 amino acids
Related rules None
Fusion None


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