HAMAP rule MF_01887
General rule information
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Accession | MF_01887 |
Dates | 8-NOV-2010 (Created) 1-JUN-2023 (Last updated, Version 13) |
Name | 23SrRNA_methyltr_B |
Scope | Bacteria; Pseudomonadota |
Template | P63177 (RLMB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Specifically methylates the ribose of guanosine 2251 in 23S rRNA. |
Catalytic activity | RHEA:24140: guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.185 |
case <OC:Enterobacterales>
Subunit | Homodimer. |
end case
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily. |
Keywords
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Gene Ontology
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GO:0070039; Molecular function: rRNA (guanosine-2'-O-)-methyltransferase activity.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Features
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From: RLMB_ECOLI (P63177) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 196 | 196 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | G | ||||||||
BINDING | 216 | 216 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [IL] | ||||||||
BINDING | 225 | 225 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [LM] |
Additional information
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Size range | 231-284 amino acids |
Related rules | None |
Fusion | None |