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HAMAP rule MF_01887

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General rule information [?]

Accession MF_01887
Dates 8-NOV-2010 (Created)
1-JUN-2023 (Last updated, Version 13)
Name 23SrRNA_methyltr_B
Scope(s) Bacteria
Template(s) P63177 (RLMB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01887 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RLMB
Protein name RecName: Full=23S rRNA (guanosine-2'-O-)-methyltransferase RlmB;
AltName: Full=23S rRNA (guanosine2251 2'-O)-methyltransferase;
AltName: Full=23S rRNA Gm2251 2'-O-methyltransferase;
Gene name Name=rlmB;

Comments [?]

FUNCTIONSpecifically methylates the ribose of guanosine 2251 in 23S rRNA.
CATALYTIC ACTIVITY Reaction=guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O- methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:24140, Rhea:RHEA-COMP:10239, Rhea:RHEA-COMP:10241, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74445; EC=;
case <OC:Enterobacterales>
end case
SIMILARITYBelongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0070039; Molecular function:rRNA (guanosine-2'-O-)-methyltransferase activity
GO:0006364; Biological process:rRNA processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00588; SpoU_methylase; 1;
Pfam PF08032; SpoU_sub_bind; 1;
NCBIfam TIGR00186; RRNA_methyl_3; 1;

Features [?]

From: RLMB_ECOLI (P63177)
Key From To Description Tag Condition FTGroup
BINDING 196 196 /ligand="S-adenosyl-L-methionine"
BINDING 216 216 /ligand="S-adenosyl-L-methionine"
BINDING 225 225 /ligand="S-adenosyl-L-methionine"

Additional information [?]

Size range 231-284 amino acids
Related rules None
Fusion Nter: None Cter: None

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