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HAMAP rule MF_01887

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General rule information [?]

Accession MF_01887
Dates 8-NOV-2010 (Created)
1-JUN-2023 (Last updated, Version 13)
Name 23SrRNA_methyltr_B
Bacteria; Pseudomonadota
Template P63177 (RLMB_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=23S rRNA (guanosine-2'-O-)-methyltransferase RlmB;
AltName: Full=23S rRNA (guanosine2251 2'-O)-methyltransferase;
AltName: Full=23S rRNA Gm2251 2'-O-methyltransferase;
Gene name

Comments [?]

Function Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
Catalytic activity RHEA:24140: guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
case <OC:Enterobacterales>
Subunit Homodimer.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0070039; Molecular function: rRNA (guanosine-2'-O-)-methyltransferase activity.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00588; SpoU_methylase; 1;
PF08032; SpoU_sub_bind; 1;
NCBIfam TIGR00186; RRNA_methyl_3; 1;

Features [?]

From: RLMB_ECOLI (P63177)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     196     196       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     G  
BINDING     216     216       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [IL]  
BINDING     225     225       /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789     [LM]  

Additional information [?]

Size range 231-284 amino acids
Related rules None
Fusion None