HAMAP rule MF_01893

General rule information [?]

Accession	MF_01893
Dates	3-MAR-2011 (Created) 1-JUN-2023 (Last updated, Version 8)

Name	Pus10_arch

Scope

Archaea

Templates

Q8U1R6 (PUS10_PYRFU); Q60346 (PUS10_METJA): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PUS10

Protein name

RecName:		Full=tRNA pseudouridine synthase Pus10;
		EC 5.4.99.25;
AltName:		Full=tRNA pseudouridine 54/55 synthase;
		Short=Psi54/55 synthase;

Gene name

pus10

Comments [?]

Function	Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
Catalytic activity	RHEA:57876: uridine(54) in tRNA = pseudouridine(54) in tRNA
	RHEA:42532: uridine(55) in tRNA = pseudouridine(55) in tRNA EC 5.4.99.25
Similarity	Belongs to the pseudouridine synthase Pus10 family.

Keywords [?]

Gene Ontology [?]

GO:0009982; Molecular function: pseudouridine synthase activity.
GO:0031119; Biological process: tRNA pseudouridine synthesis.

Cross-references [?]

Features [?]

From: PUS10_PYRFU (Q8U1R6)

Key From To Description Tag Condition FTGroup

ACT_SITE 210 210 Nucleophile D

BINDING 274 274 /ligand="substrate Y

BINDING 346 346 /ligand="substrate Y

Additional information [?]