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HAMAP rule MF_01893

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General rule information [?]

Accession MF_01893
Dates 3-MAR-2011 (Created)
1-JUN-2023 (Last updated, Version 8)
Name Pus10_arch
Templates Q8U1R6 (PUS10_PYRFU); Q60346 (PUS10_METJA): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=tRNA pseudouridine synthase Pus10;
AltName: Full=tRNA pseudouridine 54/55 synthase;
Short=Psi54/55 synthase;
Gene name

Comments [?]

Function Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
Catalytic activity RHEA:57876: uridine(54) in tRNA = pseudouridine(54) in tRNA
RHEA:42532: uridine(55) in tRNA = pseudouridine(55) in tRNA
Similarity Belongs to the pseudouridine synthase Pus10 family.

Keywords [?]

Gene Ontology [?]

GO:0009982; Molecular function: pseudouridine synthase activity.
GO:0031119; Biological process: tRNA pseudouridine synthesis.

Cross-references [?]

PROSITE PS51165; THUMP; 1; trigger=PRU00529;
Pfam PF02926; THUMP; 1;
NCBIfam TIGR01213; TIGR01213; 1;

Features [?]

From: PUS10_PYRFU (Q8U1R6)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     210     210       Nucleophile     D  
BINDING     274     274       /ligand="substrate     Y  
BINDING     346     346       /ligand="substrate     Y  

Additional information [?]

Size range 357-519 amino acids
Related rules None
Fusion None