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HAMAP rule MF_01899

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General rule information [?]

Accession MF_01899
Dates 27-MAY-2011 (Created)
1-JUN-2023 (Last updated, Version 7)
Name RNase_D
Scope(s) Bacteria
Template(s) P09155 (RND_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01899 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RND
Protein name RecName: Full=Ribonuclease D;
                 Short=RNase D;
                 EC=3.1.13.5;
Gene name Name=rnd;

Comments [?]

FUNCTIONExonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
CATALYTIC ACTIVITY Reaction=Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.; EC=3.1.13.5;
COFACTOR Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the RNase D family.

Keywords [?]


Gene Ontology [?]

GO:0033890; Molecular function:ribonuclease D activity
GO:0042780; Biological process:tRNA 3'-end processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS50967; HRDC; 1;
Pfam PF01612; DNA_pol_A_exo1; 1;
Pfam PF00570; HRDC; 1;
NCBIfam TIGR01388; Rnd; 1;

Features [?]


Additional information [?]

Size range 339-429 amino acids
Related rules None
Fusion Nter: None Cter: None



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