HAMAP rule MF_01899

General rule information [?]

Accession	MF_01899
Dates	27-MAY-2011 (Created) 1-JUN-2023 (Last updated, Version 7)

Name

RNase_D

Scope

Bacteria

Template

P09155 (RND_ECOLI)

Triggered by

HAMAP; MF_01899 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RND

Protein name

RecName:		Full=Ribonuclease D;
		Short=RNase D;
		EC 3.1.13.5;

Gene name

rnd

Comments [?]

Function	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
Catalytic activity	Reaction=Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.; EC=3.1.13.5;
Cofactor	a divalent metal cation
Subcellular location	Cytoplasm.
Similarity	Belongs to the RNase D family.

Keywords [?]

Cytoplasm
Exonuclease
Hydrolase
Nuclease
tRNA processing

Gene Ontology [?]

GO:0033890; Molecular function: ribonuclease D activity.
GO:0042780; Biological process: tRNA 3'-end processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS50967; HRDC; 1; trigger=PRU00328;
Pfam	PF01612; DNA_pol_A_exo1; 1; trigger=Yes;
	PF00570; HRDC; 1;
NCBIfam	TIGR01388; Rnd; 1;

Additional information [?]

Size range	339-429 amino acids
Related rules	None
Fusion	None

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