HAMAP rule MF_01899
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01899 |
| Accession | MF_01899 |
| Dates | 27-MAY-2011 (Created)
01-JUN-2023 (Last updated, Version 8) |
| Name | RNase_D |
| Scope(s) |
Bacteria |
| Template(s) | P09155; [ Recover all ] |
| Triggered by |
HAMAP; MF_01899 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RND |
| Protein name | RecName: Full=Ribonuclease D; Short=RNase D; EC=3.1.13.5; |
| Gene name | Name=rnd; |
Comments
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| FUNCTION | Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. |
| CATALYTIC ACTIVITY | Reaction=Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.; EC=3.1.13.5; |
| COFACTOR | Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the RNase D family. |
Keywords
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Gene Ontology
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| GO:0033890; Molecular function:ribonuclease D activity |
| GO:0042780; Biological process:tRNA 3'-end processing |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS50967; HRDC; 1; |
| Pfam | PF01612; DNA_pol_A_exo1; 1; |
| Pfam | PF00570; HRDC; 1; |
| NCBIfam | TIGR01388; Rnd; 1; |
Features
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Additional information
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| Size range | 339-429 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |