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HAMAP rule MF_01899

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General rule information [?]

Accession MF_01899
Dates 27-MAY-2011 (Created)
1-JUN-2023 (Last updated, Version 7)
Name RNase_D
Template P09155 (RND_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribonuclease D;
Short=RNase D;
Gene name

Comments [?]

Function Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
Catalytic activity Reaction=Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.; EC=;
Cofactor a divalent metal cation
Subcellular location Cytoplasm.
Similarity Belongs to the RNase D family.

Keywords [?]

Gene Ontology [?]

GO:0033890; Molecular function: ribonuclease D activity.
GO:0042780; Biological process: tRNA 3'-end processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS50967; HRDC; 1; trigger=PRU00328;
Pfam PF01612; DNA_pol_A_exo1; 1; trigger=Yes;
PF00570; HRDC; 1;
NCBIfam TIGR01388; Rnd; 1;

Additional information [?]

Size range 339-429 amino acids
Related rules None
Fusion None