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HAMAP rule MF_01902

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General rule information [?]

Accession MF_01902
Dates 28-JUN-2005 (Created)
28-NOV-2023 (Last updated, Version 22)
Name DNApol_error_prone
Scope(s) Bacteria
Actinomycetota
Planctomycetota
Pseudomonadota
Template(s) P9WNT5 (DNAE2_MYCTU); Q9A3J3 (DNAE2_CAUVC); [ Recover all ]
Triggered by HAMAP; MF_01902 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DNAE2
Protein name RecName: Full=Error-prone DNA polymerase;
                 EC=2.7.7.7;
Gene name Name=dnaE2;

Comments [?]

FUNCTIONDNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
CATALYTIC ACTIVITY Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112; EC=2.7.7.7;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the DNA polymerase type-C family. DnaE2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003887; Molecular function:DNA-directed DNA polymerase activity
GO:0006281; Biological process:DNA repair
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF07733; DNA_pol3_alpha; 1;
Pfam PF02811; PHP; 1;
Pfam PF01336; tRNA_anti; 1;
NCBIfam TIGR00594; Polc; 1;

Features [?]


Additional information [?]

Size range 1024-1195 amino acids
Related rules None
Fusion Nter: None Cter: None



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