HAMAP rule MF_01902

General rule information [?]

Accession	MF_01902
Dates	28-JUN-2005 (Created) 1-JUN-2023 (Last updated, Version 21)

Name	DNApol_error_prone

Scope

Bacteria; Actinomycetota

Bacteria; Planctomycetota

Bacteria; Pseudomonadota

Templates

P9WNT5 (DNAE2_MYCTU); Q9A3J3 (DNAE2_CAUVC): [Recover all]

Triggered by

HAMAP; MF_01902 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

DNAE2

Protein name

RecName:		Full=Error-prone DNA polymerase;
		EC 2.7.7.7;

Gene name

dnaE2

Comments [?]

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
Catalytic activity	RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1) EC 2.7.7.7
Subcellular location	Cytoplasm.
Similarity	Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Keywords [?]

Cytoplasm
DNA damage
DNA repair
DNA replication
DNA-directed DNA polymerase
Nucleotidyltransferase
Transferase

Gene Ontology [?]

GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0006281; Biological process: DNA repair.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF07733; DNA_pol3_alpha; 1;
	PF02811; PHP; 1;
	PF01336; tRNA_anti; 1;
NCBIfam	TIGR00594; Polc; 1;

Additional information [?]

Size range	1024-1195 amino acids
Related rules	None
Fusion	None

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